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M2015

Sigma-Aldrich

1-Stearoyl-rac-glycerol

≥99%

Sinónimos:

MG(18:0/0:0/0:0)[rac], 1-Monooctadecanoyl-rac-glycerol, rac-Glycerol 1-stearate, DL-α-Stearin, Monostearin

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About This Item

Fórmula lineal:
CH3(CH2)16COOCH2CH(OH)CH2OH
Número de CAS:
123-94-4
Peso molecular:
358.56
Beilstein/REAXYS Number:
1728685
EC Number:
204-664-4
MDL number:
MFCD00036186
UNSPSC Code:
51191904
PubChem Substance ID:
24896595
NACRES:
NA.25

biological source

synthetic (organic)

Quality Level

200

assay

≥99%

form

powder

functional group

phospholipid

lipid type

neutral glycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO

InChI

1S/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H3

InChI key

VBICKXHEKHSIBG-UHFFFAOYSA-N

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Application

Monostearin (1-Stearoyl-rac-glycerol) is used in the development of drug delivery vehicles such as nanoparticles and microemulsions.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Journal of drug targeting, 28(3), 259-270 (2019-09-07)
Nanocrystals and lipid-based nanosystems have the potential to play a crucial role in a significant shift in the treatment of ophthalmic diseases. These drug delivery systems allow overcoming the barriers imposed by anatomy and physiology of the organ of vision.
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International journal of pharmaceutics, 532(1), 612-622 (2017-09-25)
The oral uptake of intact nanocarriers through Peyer's patches is an important uptake pathway. We report Rifampicin Lipid-Polymer hybrid nanoparticles (RIF-LIPOMER) using glyceryl monostearate as lipid and the mucoadhesive polymer, Gantrez, with the objective of balancing hydrophobicity and mucoadhesion for
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Drug delivery, 23(9), 3181-3192 (2016-03-05)
Statins proved potential bone healing properties. Rosuvastatin is a synthetic, hydrophilic, potent and highly efficacious statin. In the current work, an attempt was investigated to develop, evaluate various bioerodible composite sponges enclosing rosuvastatin and explore their potential in augmenting bone
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Multiple sclerosis (MS) is a chronic, autoimmune, neurodegenerative disease of the central nervous system (CNS) that yields to neuronal axon damage, demyelization, and paralysis. Although several drugs were designed for the treatment of MS, with some of them being approved
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Objective: The aim of the present investigation was to investigate the efficacy of solid lipid nanoparticles (SLNs) to enhance the absorption and bioavailability of lurasidone hydrochloride (LH) following oral administration. Methods: The LH loaded SLNs (LH-SLNs) were prepared by high
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