E9505

β-Estradiol 3-sulfate sodium salt

≥93%

• Sinónimos: 1,3,5(10)-Estratriene-3,17β-diol 3-sulfate, 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-sulfate
• Fórmula lineal: C₁₈H₂₃O₅SNa
• Número de CAS: 4999-79-5
• Peso molecular: 374.43
• Número MDL: MFCD00056553
• Código UNSPSC: 51111800
• ID de la sustancia en PubChem: 24894699
• NACRES: NA.77

Propiedades

• esterilidad: non-sterile
• Nivel de calidad: 200
• Ensayo: ≥93%
• Formulario: powder
• contiene: ~70% N-methyl-D-glucamine as stabilizer
• solubilidad: methanol: 9.80-10.20 mg/mL, clear, colorless to faintly yellow
• Condiciones de envío: ambient
• temp. de almacenamiento: room temp
• cadena SMILES: [Na].[H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])CCc4cc(OS(O)(=O)=O)ccc24
• InChI: 1S/C18H24O5S.Na.H/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;;/h3,5,10,14-17,19H,2,4,6-9H2,1H3,(H,20,21,22);;/t14-,15-,16+,17+,18+;;/m1../s1
• Clave InChI: PYPVMTJYMKHIST-LBARCDFESA-N

Descripción

Descripción general

β-Estradiol is secreted by developing ovaries and is predominant during premenopause in women.

Aplicación

β-Estradiol 3-sulfate sodium salt has been used to measure the estradiol level from culture supernatant in ultra-performance liquid chromatography-tandem mass spectrometry.

Acciones bioquímicas o fisiológicas

β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, hence it is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.

Envase

Package size based on steroid content

Información de seguridad

• Pictogramas: GHS08,GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302 + H332,H351
• Consejos de prudencia: P202 - P261 - P264 - P301 + P312 - P304 + P340 + P312 - P308 + P313
• Clasificaciones de peligro: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges