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A9736

Sigma-Aldrich

A-438079 hydrochloride hydrate

≥98% (HPLC)

Sinónimos:

3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methyl pyridine hydrochloride hydrate

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About This Item

Fórmula empírica (notación de Hill):
C13H9Cl2N5·HCl · xH2O
Número de CAS:
899431-18-6
Peso molecular:
342.61 (anhydrous basis)
MDL number:
MFCD17215929
UNSPSC Code:
12352200
PubChem Substance ID:
329771058
NACRES:
NA.77

Quality Level

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 20 mg/mL, clear

originator

Abbott

storage temp.

2-8°C

SMILES string

O.Cl.Clc1cccc(c1Cl)-c2nnnn2Cc3cccnc3

InChI

1S/C13H9Cl2N5.ClH.H2O/c14-11-5-1-4-10(12(11)15)13-17-18-19-20(13)8-9-3-2-6-16-7-9;;/h1-7H,8H2;1H;1H2

InChI key

ZHFJJBAKSROKNO-UHFFFAOYSA-N

Application

A-438079 hydrochloride hydrate has been used to determine its inhibitory effect on purinergic receptors. It has also been used to check its inhibitory effects on macrophages.

Biochem/physiol Actions

A-438079 hydrochloride hydrate is a selective P2X7 purinoceptor antagonist in both human and rat with minimal activity at 75 different G-protein-coupled receptors, enzymes, transporters, and ion channels tested.

Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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