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Merck
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Key Documents

A1345

Sigma-Aldrich

Antioxidant Supplement (1000×)

liquid, sterile-filtered, suitable for cell culture

Sinónimos:

Antioxidant Solution

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About This Item

UNSPSC Code:
12352205
NACRES:
NA.75

sterility

sterile-filtered

Quality Level

form

liquid

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

shipped in

ambient

storage temp.

2-8°C

General description

Antioxidant Supplement (1000×) is a proprietary medium supplement specially formulated to boost cell growth for enhanced viral and protein expression. It may be used in combination with Polyamine Supplement (P 8483).
One mL supplements 1 liter of medium.

Application

Antioxidant Supplement (1000×) has been used:

  • as a component of the extender media for dilution of sperm samples during cryopreservation
  • for long term culture of human-induced pluripotent stem (iPS) cells
  • as a component of the immortalization media used for culturing, cloning and expansion of clones for making immortalized cell lines from embryonic mouse kidney

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


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E Cabrita et al.
Animal reproduction science, 125(1-4), 189-195 (2011-04-13)
During cryopreservation, dilution in the extender media reduces the seminal plasma constituents being cells more vulnerable to oxidative stress. Vitamins (C and E) and the amino acids taurine and hypotaurine are powerful antioxidants naturally present in seminal plasma. Whether their
Lan Luo et al.
Scientific reports, 4, 3779-3779 (2014-01-22)
Effects of antioxidants on the quality and genomic stability of induced pluripotent stem (iPS) cells were investigated with two human iPS cell lines (201B7 and 253G1). Cells used in this study were expanded from a single colony of each cell
Michael R Duggan et al.
Cell death discovery, 7(1), 60-60 (2021-03-28)
Despite increasing numbers of aged individuals living with HIV, the mechanisms underlying HIV-associated neurological disorders (HANDs) remain elusive. As HIV-1 pathogenesis and aging are characterized by oxidative stress as well as altered protein quality control (PQC), reactive oxygen species (ROS)
Tullia Maraldi et al.
Rejuvenation research, 23(2), 93-106 (2019-08-02)
The efficient use of stem cells for transplantation is often limited by the relatively low number of stem cells collected. The ex vivo expansion of human stem cells for clinical use is a potentially valuable approach to increase stem cell
Kendall Mitchell et al.
BMC neuroscience, 17(1), 80-80 (2016-12-03)
Bone morphogenetic protein-2 (BMP-2) is a pleiotropic, secreted molecule with diverse effects. The potent ability of BMP-2 to stimulate bone growth prompted its widespread clinical use for arthrodesis (spine fusion). However, elevated post-operative pain in patients treated with BMP-2 has

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