6906-50A

Human Peripheral Blood Monocytes: HPBM

• Sinónimos: HPBM, HPBM cells
• Código UNSPSC: 41106514
• NACRES: NA.81

Propiedades

• origen biológico: human peripheral blood
• Formulario: liquid
• envase: pkg of 5,000,000 cells
• fabricante / nombre comercial: Cell Applications, Inc
• modo de crecimiento: Suspension
• técnicas: cell culture | mammalian: suitable
• Condiciones de envío: dry ice
• temp. de almacenamiento: −196°C

Descripción

Descripción general

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Human Peripheral Blood Monocytes (HPBM) provide a useful in vitro tool for studying various aspects of pathology and biology. Our CD14⁺ Monocytes are isolated and purified from human peripheral blood of healthy donors and cryopreserved immediately after isolation.

HPBM are the precursors of tissue macrophages and dentritic cells and are central to immunological responses, including cell-mediated cytotoxicity and production of inflammatory mediators. The CD14 monocyte subset expresses a component of the lipopolysaccharide (LPS) receptor complex, are large with diameter of ~18 um, represent ~80%–90% of circulating monocytes, and express higher levels of CD62L (L-selectin) and CD11b (also referred to as Mac-1 or CR3) and lower levels of MHC class II than do CD16+ monocytes.

Origen línea celular

Blood

Aplicación

Immune system dysfunction. Immunological responses, cell-mediated cytotoxicity, production of inflammatory mediators, hematopoiesis, myeloid differentiation, lipopolysaccharide (LPS), receptor complexes, CD62L (L-selectin), CD11b (Mac-1 or CR3), MHC class II.

Envase

Immediately after isolation, 5,000,000 cells in DMEM containing 45% FBS & 10% DMSO.

Componentes

DMEM containing 45% FBS & 10% DMSO

Calidad

Each lot was tested for proper morphology, CD14 positive selection, Negative for HIV, Hepatitis B, Hepatitis C

Cláusula de descargo de responsabilidad

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable