460R-1

Heat Shock Protein 70 (EP377) Rabbit Monoclonal Primary Antibody

• UNSPSC Code: 12352203

Propiedades

• biological source: rabbit
• Quality Level: 100; 500
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: EP377, monoclonal
• description: For In Vitro Diagnostic Use in Select Regions
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (460R-14); vial of 0.1 mL concentrate Research Use Only (460R-14-RUO); vial of 0.5 mL concentrate (460R-15); vial of 1.0 mL concentrate (460R-16); vial of 1.0 mL concentrate Research Use Only (460R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (460R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (460R-17); vial of 7.0 mL pre-dilute ready-to-use (460R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (460R-18-RUO)
• manufacturer/tradename: Cell Marque^™
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• isotype: IgG
• control: hepatocellular carcinoma
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: cytoplasmic, nuclear
• Gene Information: human ... HSPA1A(3303)

Descripción

General description

The Heat Shock Protein 70 family of highly conserved chaperone proteins increase in expression upon exposure to stress factors such as temperature shock, hypoxia, oxidative stress, and pH change. This promotes cell survival by repairing misfolded proteins and preventing protein aggregates, among other functions. Likewise, tumor cells can use this mechanism to confer a survival advantage as demonstrated in Heat Shock Protein 70 overexpression in hepatocellular carcinoma.

Quality

United States - IVD
European Union - IVD
Japan - RUO

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2