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Merck

P1386

Sigma-Aldrich

Propionic acid

≥99.5%

Sinónimos:

Acid C3, Propanoic acid, Propanyl acid

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About This Item

Fórmula lineal:
CH3CH2COOH
Número de CAS:
Peso molecular:
74.08
Beilstein/REAXYS Number:
506071
EC Number:
MDL number:
UNSPSC Code:
12352106
eCl@ss:
39021305
PubChem Substance ID:
NACRES:
NA.21

vapor density

2.55 (vs air)

Quality Level

vapor pressure

2.4 mmHg ( 20 °C)

assay

≥99.5%

autoignition temp.

955 °F

expl. lim.

12.1 %

impurities

≤0.25% water (Karl Fischer)

color

≤10, APHA:

refractive index

n20/D 1.386 (lit.)

bp

141 °C (lit.)

mp

−24-−23 °C (lit.)

density

0.993 g/mL at 25 °C (lit.)

SMILES string

CCC(O)=O

InChI

1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)

InChI key

XBDQKXXYIPTUBI-UHFFFAOYSA-N

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General description

Propionic acid (PA) is a naturally occurring carboxylic acid, which in its pure state exists as a colorless corrosive liquid with an unpleasant odor. It is miscible in water. Industrially it is produced by hydrocarboxylation of ethylene in presence nickel carbonyl as a catalyst. PA has been found to reduce food intake, lower the fatty acids content in plasma and liver, might improve tissue insulin sensitivity and exerts immunosuppressive actions. Propionic acid is an excellent raw material as it is stable, cheap and safe and can even be used as a food additive.

Application


  • Distribution Characteristics of Low-Molecular-Weight Organic Acids in Reclaimed Soil Filled with Fly Ash: A Study.: This research investigates the presence and distribution of propionic acid among other organic acids in reclaimed soils treated with fly ash. The study provides insights into the environmental impact and potential remediation strategies for soils contaminated with industrial by-products (Zheng et al., 2024).

  • Effects of Black Soldier Fly (Hermetia illucens L., BSF) Larvae Addition on In Vitro Fermentation Parameters of Goat Diets.: This study examines how the addition of black soldier fly larvae affects the fermentation process of goat diets, including the production of propionic acid. The findings suggest potential benefits for improving animal nutrition and gut health (Lu et al., 2024).

  • NMR Spectroscopy in Diagnosis and Monitoring of Methylmalonic and Propionic Acidemias.: This review highlights the use of NMR spectroscopy to diagnose and monitor methylmalonic and propionic acidemias, providing a non-invasive method for tracking these metabolic disorders. The study underscores the clinical significance of propionic acid in metabolic research (Deleanu & Nicolescu, 2024).

  • The New Buffer Salt-Protected Sodium Butyrate Promotes Growth Performance by Improving Intestinal Histomorphology, Barrier Function, Antioxidative Capacity, and Microbiota Community of Broilers.: This study explores how propionic acid, along with sodium butyrate, improves the growth performance and gut health of broilers. The research demonstrates the beneficial effects of these acids on poultry farming (Melaku et al., 2024).

  • Prevotella enterotype associates with diets supporting acidic faecal pH and production of propionic acid by microbiota.: This study links the presence of the Prevotella enterotype in the gut microbiota to diets that promote the production of propionic acid, emphasizing the role of diet in modulating gut health and metabolic functions (Adamberg & Adamberg, 2024).


signalword

Danger

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

129.2 °F - closed cup

flash_point_c

54 °C - closed cup


Certificados de análisis (COA)

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Kaori Watanabe et al.
Cell reports, 28(10), 2594-2607 (2019-09-05)
During evolution, organisms have acquired variable feeding habits. Some species are nutritional generalists that adapt to various food resources, while others are specialists, feeding on specific resources. However, much remains to be discovered about how generalists adapt to diversified diets.
Jialin Liu et al.
BMC biology, 18(1), 129-129 (2020-09-21)
The evolution of embryological development has long been characterized by deep conservation. In animal development, the phylotypic stage in mid-embryogenesis is more conserved than either early or late stages among species within the same phylum. Hypotheses to explain this hourglass
Maria Litovchenko et al.
Science advances, 7(5) (2021-01-31)
Natural genetic variation affects circadian rhythms across the evolutionary tree, but the underlying molecular mechanisms are poorly understood. We investigated population-level, molecular circadian clock variation by generating >700 tissue-specific transcriptomes of Drosophila melanogaster (w1118 ) and 141 Drosophila Genetic Reference
Maria Elena Martino et al.
Cell host & microbe, 24(1), 109-119 (2018-07-17)
Animal-microbe facultative symbioses play a fundamental role in ecosystem and organismal health. Yet, due to the flexible nature of their association, the selection pressures that act on animals and their facultative symbionts remain elusive. Here we apply experimental evolution to
Nucleophilic ?-Carbon Activation of Propionic Acid as a 3-Carbon Synthon by Carbene Organocatalysis
Jin, Zhichao, et al.
Chemistry?A European Journal , 21 (26), 9360-9363 (2015)

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