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Key Documents

Y0000612

Dopexamine dihydrochloride

European Pharmacopoeia (EP) Reference Standard

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About This Item

Fórmula empírica (notación de Hill):
C22H32N2O2 · 2HCl
Número de CAS:
86484-91-5
Peso molecular:
429.42
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

dopexamine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C22H32N2O2.2ClH/c25-21-11-10-20(18-22(21)26)13-17-24-15-7-2-1-6-14-23-16-12-19-8-4-3-5-9-19;;/h3-5,8-11,18,23-26H,1-2,6-7,12-17H2;2*1H

Inchi Key

VPDULUNRSQWWJB-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dopexamine dihydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Reiner Oberbeck
Current medicinal chemistry, 13(17), 1979-1989 (2006-07-18)
The existence of an immune-endocrine interaction has been reported and the modulatory effects of the natural occurring catecholamines epinephrine, norepinephrine and dopamine as well as of pharmaceutically generated catecholamines like dopexamine on a wide variety of immune functions were demonstrated.
Philippe Seguin et al.
Critical care (London, England), 10(1), R32-R32 (2006-03-02)
Microcirculatory blood flow, and notably gut perfusion, is important in the development of multiple organ failure in septic shock. We compared the effects of dopexamine and norepinephrine (noradrenaline) with those of epinephrine (adrenaline) on gastric mucosal blood flow (GMBF) in
N E El Mokhtari et al.
European journal of medical research, 13(10), 459-463 (2008-11-15)
To examine the effects of a therapy with dopexamine/dopamine in comparison with a regimen of dobutamine/dopamine on the outcome of patients with profound cardiogenic shock. Twenty patients presenting with an acute cardiogenic shock assisted with mechanical ventilation, being refractory to
Nour Eddine El Mokhtari et al.
European journal of medical research, 12(11), 563-567 (2007-11-21)
To examine the effects of a therapy with dopexamine/dopamine in comparison with a regimen of dobutamine/dopamine on the outcome of patients with profound cardiogenic shock. Twenty patients presenting with an acute cardiogenic shock assisted with mechanical ventilation, being refractory to
Dopexamine and survival: areas of consistency.
R Pearse et al.
Anaesthesia, 64(11), 1258-1258 (2009-10-15)
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