PHR2408

N-Nitrosodiethylamine

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: N-Nitrosodiethylamine, Diethylnitrosamine
• Fórmula lineal: (C₂H₅)₂NNO
• Número de CAS: 55-18-5
• Peso molecular: 102.14
• Beilstein: 1744991
• Número MDL: MFCD00013890
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: certified reference material; pharmaceutical secondary standard
• Nivel de calidad: 300
• Agency: traceable to USP 1466652
• Formulario: liquid
• CofA: current certificate can be downloaded
• envase: pkg of 1 g
• bp: 177 °C (lit.)
• densidad: 0.95 g/mL (lit.)
• aplicaciones: pharmaceutical
• temp. de almacenamiento: 2-30°C
• cadena SMILES: CCN(CC)N=O
• InChI: 1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3
• Clave InChI: WBNQDOYYEUMPFS-UHFFFAOYSA-N

Descripción

Descripción general

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicación

N-Nitrosodiethylamine (NDEA) pharmaceutical secondary referencestandard is used to determine NDEA impurity in:

• Lisinopril API and its final product[1]
• Sitagliptin and metformin hydrochlorideimmediate and extended-release formulations[2]

These Secondary Standards are qualified as Certified ReferenceMaterials. These are suitable for use in several analytical applicationsincluding but not limited to pharma release testing, pharma method developmentfor qualitative and quantitative analyses, food and beverage quality controltesting, and other calibration requirements.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAC4356 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Información de seguridad

• Pictogramas: GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H301,H350,H412
• Consejos de prudencia: P202 - P264 - P270 - P273 - P280 - P301 + P310
• Clasificaciones de peligro: Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable