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Merck

PHR1274

Supelco

Melamine

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

2,4,6-Triamino-1,3,5-triazine, sym-Triaminotriazine

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About This Item

Fórmula empírica (notación de Hill):
C3H6N6
Número de CAS:
Peso molecular:
126.12
Beilstein:
124341
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

certified reference material
pharmaceutical secondary standard

Nivel de calidad

Agency

traceable to USP 1379183

familia API

melamine

CofA

current certificate can be downloaded

técnicas

HPLC: suitable
gas chromatography (GC): suitable

mp

>300 °C (lit.)

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-30°C

cadena SMILES

Nc1nc(N)nc(N)n1

InChI

1S/C3H6N6/c4-1-7-2(5)9-3(6)8-1/h(H6,4,5,6,7,8,9)

Clave InChI

JDSHMPZPIAZGSV-UHFFFAOYSA-N

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Descripción general

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Melamine is a nitrogen-rich chemical employed in the production of plastics, resins, laminates, adhesives as well as flame retardants. It may also be utilized as a fertilizer. It is one of the metabolites of cyromazine, which is approved for use as an insecticide on a wide range of vegetable crops.

Aplicación

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAC3464 in the slot below. This is an example certificate only and may not be the lot that you receive.

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogramas

Health hazard

Palabra de señalización

Warning

Frases de peligro

Clasificaciones de peligro

Carc. 2 - Repr. 2 - STOT RE 2

Órganos de actuación

Urinary tract

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

572.0 °F - closed cup

Punto de inflamabilidad (°C)

300 °C - closed cup


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Certificados de análisis (COA)

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Method development and validation for melamine and its derivatives in rice concentrates by liquid chromatography. Application to animal feed samples
Mu?iz-Valencia R, et al.
Analytical and Bioanalytical Chemistry, 392(3), 523-531 (2008)
Hui Yang et al.
Nano letters, 15(3), 1730-1735 (2015-02-11)
We detect by optical microscopy Au and fluorescent nanoparticles (NPs) during their motion in water-based medium, using an array of dielectric microspheres that are patterned in a microwell array template. The microspheres act as lenses focusing the light originating from
Ana Paula Craig et al.
Annual review of food science and technology, 4, 369-380 (2013-01-10)
Surface-enhanced Raman spectroscopy (SERS) is an advanced Raman technique that enhances the vibrational spectrum of molecules adsorbed on or in the vicinity of metal particles and/or surfaces. Because of its readiness, sensitivity, and minimum sample preparation requirements, SERS is being
Lei An et al.
Neurobiology of learning and memory, 100, 18-24 (2012-12-13)
Our previous studies reported that hippocampus was one of the target sites of melamine, by which the spatial cognition and hippocampal long-term potentiation (LTP) could be impaired. The aim of present study was to investigate whether cognitive behavior impairment induced
Vivek Bhalla et al.
Kidney international, 75(8), 774-779 (2009-02-13)
Recent outbreaks of nephrolithiasis and acute kidney injury among children in China have been linked to ingestion of milk-based infant formula contaminated with melamine. These cases provide evidence in humans for the nephrotoxicity of melamine, which previously had been described

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