N9890

Norfloxacin

analytical standard, ≥98% (TLC)

• Sinónimos: 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-3-quinolinecarboxylic acid
• Fórmula empírica (notación de Hill): C₁₆H₁₈FN₃O₃
• Número de CAS: 70458-96-7
• Peso molecular: 319.33
• EC Number: 274-614-4
• MDL number: MFCD00079532
• UNSPSC Code: 41116107
• PubChem Substance ID: 329818696
• NACRES: NA.24

Propiedades

• grade: analytical standard
• Quality Level: 200
• agency: EPA 1694
• assay: ≥98% (TLC)
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): clinical testing
• format: neat
• storage temp.: 2-8°C
• SMILES string: CCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCNCC3
• InChI: 1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
• Inchi Key: OGJPXUAPXNRGGI-UHFFFAOYSA-N
• Gene Information: human ... CYP1A2(1544) ; rat ... Gabra1(29705)

Descripción

General description

Chemical structure: fluoroquinolone

Norfloxacin is a broad spectrum antibiotic, which is used against a wide variety of gram positive and gram negative bacteria.

Application

Norfloxacin may be used as a standard in the determination of norfloxacin in human serum samples using fluorometric spectrophotometry.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Norfloxacin blocks DNA replication by interfering with an ATP-induced structural transition of DNA complexed with DNA gyrase (topoisomerase).
Mode of action: inhibits bacterial DNA replication
Antimicrobial spectrum: Gram-negative bacteria; less effective against Gram-positive bacteria

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)