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Key Documents

M1808000

Metixene hydrochloride

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Methixene monohydrochloride monohydrate

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About This Item

Fórmula empírica (notación de Hill):
C20H23NSl · HCl · H2O
Número de CAS:
7081-40-5
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

metixene

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C20H23NS.ClH.H2O/c1-21-12-6-7-15(14-21)13-18-16-8-2-4-10-19(16)22-20-11-5-3-9-17(18)20;;/h2-5,8-11,15,18H,6-7,12-14H2,1H3;1H;1H2

InChI key

RAOHHYUBMJLHNC-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Metixene hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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JAMA, 195(10), 851-851 (1966-03-07)
Methixene hydrochloride, an anticholinergic agent, may be useful in the symptomatic treatment of functional bowel disorders. Adverse effects reported from its use are those of the anticholinergic drugs in general.
[An anticholinergic agent, the side effect of mouth dryness and hazards for the teeth].
W H van Palenstein Helderman et al.
Nederlands tijdschrift voor geneeskunde, 127(51), 2318-2321 (1983-12-17)
M I Walash et al.
Pharmaceutisch weekblad. Scientific edition, 8(4), 234-238 (1986-08-22)
A simple and rapid colorimetric method for the quantitative determination of the thioxanthene derivatives, chlorprothixene, tiotixene and metixene has been performed either in their pure form or in tablets. The procedure is based upon the formation of charge transfer complexes
P A Fischer et al.
Journal of neural transmission. Supplementum, 25, 137-147 (1987-01-01)
To quantify the clinical benefit of an additional deprenyl administration in L-dopa pretreated patients we have performed a study of 30 patients suffering from advanced parkinsonism. During the first phase of the study over three months under controlled conditions deprenyl
[The treatment of Parkinson tremors and forms of extrapyramidal tremors with methixene. A multicenter study].
E Volles et al.
Die Medizinische Welt, 34(24), 707-709 (1983-06-17)
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