G7776

Glutaraldehyde solution

Grade I, 70% in H₂O, specially purified for use as an electron microscopy fixative or other sophisticated use

• Sinónimos: Glutaric dialdehyde solution, Pentane-1,5-dial
• Fórmula lineal: OHC(CH₂)₃CHO
• Número de CAS: 111-30-8
• Peso molecular: 100.12
• Beilstein/REAXYS Number: 605390
• MDL number: MFCD00007025
• UNSPSC Code: 12352114
• PubChem Substance ID: 24895322
• NACRES: NA.21

Propiedades

• Quality Level: 200
• type: Grade I
• form: liquid
• concentration: 70% in H₂O
• technique(s): electron microscopy: suitable (fixative)
• color: colorless
• solubility: water: soluble
• storage temp.: −20°C
• SMILES string: [H]C(CCCC([H])=O)=O
• InChI: 1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2
• InChI key: SXRSQZLOMIGNAQ-UHFFFAOYSA-N

Descripción

General description

Glutaraldehyde is a fixative used in electron microscopy. It is a rapidly penetrating fixative and an alternative to the expensive and toxic buffered osmium tetroxide. Glutaraldehyde contains two aldehyde group separated by three methylene bridges. It mediates protein crosslinking at their amino groups.[1]

Application

Glutaraldehyde solution has been used as a fixative for transfected adherent monkey kidney fibroblasts (COS-7) cells for electron microscopy studies,[2] human osteosarcoma (U2OS) cells for super-resolution (SR) experiments[3] and for hydrogels for scanning electron microscopy (SEM) studies.[4]

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Información de seguridad

• pictograms: GHS06,GHS08,GHS05,GHS09
• signalword: Danger
• hcodes: H301,H314,H317,H330,H334,H335,H410
• pcodes: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• supp_hazards: EUH071
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter