C3607

Vitamina B₁₂

meets USP testing specifications

• Sinónimos: α-(5,6-Dimetilbencimidazolil)cianocobamida, CN-Cbl, Cianocob(III)alamina, Cianocobalamina
• Fórmula empírica (notación de Hill): C₆₃H₈₈CoN₁₄O₁₄P
• Número de CAS: 68-19-9
• Peso molecular: 1355.37
• Beilstein/REAXYS Number: 4122889
• EC Number: 200-680-0
• UNSPSC Code: 12352205
• eCl@ss: 34058004
• PubChem Substance ID: 24892627
• NACRES: NA.21

Propiedades

• agency: USP/NF; meets USP testing specifications
• Quality Level: 200
• assay: 96.0-102.0% dry basis
• form: powder
• color: dark red
• application(s): pharmaceutical (small molecule)
• storage temp.: 2-8°C
• SMILES string: C/C(C1=N[C@]([C@]([C@H](CC(N)=O)[C@@]/2(C)CCC(NC[C@@H](OP([O-])(O[C@H]3[C@@H](O)[C@@H](N4C=[N]5C6=C4C=C(C)C(C)=C6)O[C@@H]3CO)=O)C)=O)([H])N([Co+]5C#N)C2=C(C)/C([C@@H](CCC(N)=O)C/7(C)C)=NC7=C/8)(C)[C@@](C)(CC(N)=O)[C@@H]1CCC(N)=O)=C9N=C8[C@@H](CCC(N)=O)[C@
• InChI: 1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;;+2/p-2/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57?,59-,60+,61+,62+;;/m1../s1
• InChI key: RMRCNWBMXRMIRW-QJRSUKKJSA-L

Descripción

General description

Cyanocobalamin (B₁₂) is a water soluble vitamin, which is mainly found in animal products, like dairy products, meat and eggs. It belongs to the B₁₂ class of vitamins, commonly called as cobalamins. Cyanocobalamin consists of four pyrrole rings with a central cobalt atom coordinated by four equatorial nitrogen ligands.

Application

Cyanocobalamin has been used to study its effects on the prevention of colon cancer.

Required for growth, genetic stability and survival of cells in vitro. Functions to support one-carbon metabolism. Present in many classical and serum-free formulations.

Biochem/physiol Actions

Cyanocobalamin is used in the preparation of multivitamin supplements and fortified food. It acts as a coenzyme to convert L-methylmalonyl CoA to succinyl CoA, which is catalyzed by isomerase. Cyanocobalamin is used to treat vitamin B₁₂ deficiency. Cyanocobalamin meets USP testing specifications.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• ppe: Eyeshields, Gloves, type N95 (US)