BP854

Chloramphenicol

British Pharmacopoeia (BP) Reference Standard

• Sinónimos: D-(−)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide, D-(−)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol, D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide, Chloromycetin
• Fórmula lineal: Cl₂CHCONHCH(CH₂OH)CH(OH)C₆H₄NO₂
• Número de CAS: 56-75-7
• Peso molecular: 323.13
• Beilstein: 2225532
• Número CE: 200-287-4
• Número MDL: MFCD00078159
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: chloramphenicol
• Formulario: powder
• caducidad: limited shelf life, expiry date on the label
• fabricante / nombre comercial: BP
• mp: 149-153 °C (lit.)
• aplicaciones: pharmaceutical; pharmaceutical small molecule
• Formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)c1ccc(cc1)[N+]([O-])=O
• InChI: 1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1
• Clave InChI: WIIZWVCIJKGZOK-RKDXNWHRSA-N

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Chloramphenicol BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Chloramphenicol Eye Drops

Chloramphenicol Sodium Succinate Injection

Chloramphenicol Capsules

Chloramphenicol Ear Drops

Chloramphenicol Eye Ointment

Acciones bioquímicas o fisiológicas

Modo de acción: Inhibe la traducción en las subunidades de ribosomas 50S en la peptidiltransferasa (inhibición de elongación). Bacteriostático.
Modo de resistencia: Acetilación por cloranfenicol-acetiltransferasa (gen cat).

Envase

Unit quantity: 500 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08,GHS05
• Palabra de señalización: Danger
• Frases de peligro: H318,H351,H361fd
• Consejos de prudencia: P202 - P280 - P305 + P351 + P338 - P308 + P313 - P405 - P501
• Clasificaciones de peligro: Carc. 2 - Eye Dam. 1 - Repr. 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3