80154
Dipentyl phthalate
Selectophore™, ≥99.0%
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About This Item
Fórmula empírica (notación de Hill):
C18H26O4
Número de CAS:
Peso molecular:
306.40
Beilstein/REAXYS Number:
1987323
EC Number:
MDL number:
UNSPSC Code:
26111700
PubChem Substance ID:
NACRES:
NB.61
Productos recomendados
grade
for ion-selective electrodes
Quality Level
product line
Selectophore™
assay
≥99.0% (GC)
≥99.0%
form
liquid
refractive index
n20/D 1.490
density
1.025 g/mL at 20 °C (lit.)
SMILES string
CCCCCOC(=O)c1ccccc1C(=O)OCCCCC
InChI
1S/C18H26O4/c1-3-5-9-13-21-17(19)15-11-7-8-12-16(15)18(20)22-14-10-6-4-2/h7-8,11-12H,3-6,9-10,13-14H2,1-2H3
InChI key
IPKKHRVROFYTEK-UHFFFAOYSA-N
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General description
Dipentyl phthalate (DPeP) belongs to phthalate group, and is a dialkyl or aryl/alkyl diesters of phthalic acid. It may be prepared from phthalic anhydride along with n-pentanol.
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Application
- Biologically relevant reductions in fetal testosterone and Insl3 induced by in utero exposure to high levels of di-isononyl phthalate (DINP) in male rats: Dipentyl phthalate′s structural similarities to DINP underpin studies on phthalate exposure′s impacts on male reproductive health, providing insights into potential risks and mechanisms of toxicity in developmental stages (Earl Gray L Jr, 2023).
- Exposure to dipentyl phthalate in utero disrupts the adrenal cortex function of adult male rats by inhibiting SIRT1/PGC-1α and inducing AMPK phosphorylation: This study uses dipentyl phthalate to examine the adverse effects of phthalate exposure on adrenal gland function, contributing to a deeper understanding of metabolic disruptions (Chen et al., 2023).
- Determination of 15 phthalic acid esters based on GC-MS/MS coupled with modified QuEChERS in edible oils: This research demonstrates the utility of dipentyl phthalate in method development for detecting phthalates in food matrices, enhancing food safety assessments (Wang et al., 2022).
- Development of a putative adverse outcome pathway network for male rat reproductive tract abnormalities with specific considerations for the androgen sensitive window of development: Dipentyl phthalate is investigated for its role in developmental toxicity, aiding in the construction of models predicting reproductive health effects from chemical exposures (Palermo et al., 2021).
Other Notes
Plasticizer for PVC membrane electrodes
Legal Information
Selectophore is a trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Repr. 1B
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk_germany
WGK 3
flash_point_f
244.4 °F - closed cup
flash_point_c
118 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Los clientes también vieron
M.M. Khalil
Analytical Letters, 26, 2071-2071 (1993)
D M Creasy et al.
Experimental and molecular pathology, 46(3), 357-371 (1987-06-01)
A sequential morphological study has been carried out to examine the ultrastructural effects of di-n-pentyl phthalate (DPP) on the mature rat testis. A single oral dose of 2.2 g DPP/kg body wt was administered, and testes, perfuse-fixed 3-48 hr after
J J Heindel et al.
Toxicology and applied pharmacology, 97(2), 377-385 (1989-02-01)
High doses of phthalate esters in vivo cause testicular lesions. One initial target for these effects is the sustentacular Sertoli cell. Sertoli cells are unique in that they have surface membrane receptors for follicle-stimulating hormone (FSH), which couple to adenylate
N P Moore et al.
Archives of toxicology, 66(6), 435-442 (1992-01-01)
Cell-specific testicular toxicants have been used to examine the distribution of creatine within the rat testis, and to examine the potential use of creatinuria as a non-invasive indicator of testicular damage. Groups of rats were administered single doses of various
Changes in ultrastructure and cytochemical localization of zinc in rat testis following the administration of di-n-pentyl phthalate.
P M Foster et al.
Toxicology and applied pharmacology, 63(1), 120-132 (1982-03-30)
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