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Key Documents

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50787

Supelco

Bisoprolol

analytical standard

Sinónimos:

1-{4-{[2-(1-Methylethoxy)ethoxy]methyl}phenoxy}-3-[(1-methylethyl)amino]-2-propanol

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About This Item

Fórmula empírica (notación de Hill):
C18H31NO4
Número de CAS:
66722-44-9
Peso molecular:
325.44
MDL number:
MFCD00865795
UNSPSC Code:
41116107
PubChem Substance ID:
329757631
NACRES:
NA.24

grade

analytical standard

assay

≥97.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(C)OCCOCC1=CC=C(OCC(O)CNC(C)C)C=C1

InChI

1S/C18H31NO4/c1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4/h5-8,14-15,17,19-20H,9-13H2,1-4H3

InChI key

VHYCDWMUTMEGQY-UHFFFAOYSA-N

Gene Information

human ... ADRB1(153)

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2 - STOT RE 2

target_organs

Heart

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
BCCL9762
BCCK9254
BCCG9195
BCCF5130
BCCD9646

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An S De Vriese et al.
Journal of the American Society of Nephrology : JASN, 31(1), 186-196 (2019-11-11)
Vitamin K antagonists (VKAs), although commonly used to reduce thromboembolic risk in atrial fibrillation, have been incriminated as probable cause of accelerated vascular calcification (VC) in patients on hemodialysis. Functional vitamin K deficiency may further contribute to their susceptibility for
Syunsuke Yamamoto et al.
Journal of pharmaceutical sciences, 106(9), 2787-2794 (2017-03-21)
Although several mathematical models have been reported for the estimation of human plasma concentration profiles of drug substances after dermal application, the successful cases that can predict human pharmacokinetic profiles are limited. Therefore, the aim of this study is to
Gyung Min Park et al.
Diabetes & metabolism journal, 44(3), 470-479 (2019-11-27)
There are limited data on the impact of diabetes control on the risk of subclinical coronary atherosclerosis. We analyzed 6,434 consecutive asymptomatic individuals without previous history of coronary artery disease who underwent coronary computed tomographic angiography (CCTA) (mean age, 53.7±7.6
Peter C Rockers et al.
The Lancet. Global health, 7(4), e492-e502 (2019-02-26)
Novartis Access is a Novartis programme that offers a portfolio of non-communicable disease medicines at a wholesale price of US$1 per treatment per month in low-income and middle-income countries. We evaluated the effect of Novartis Access in Kenya, the first
Lauri Suojanen et al.
Basic & clinical pharmacology & toxicology, 121(2), 130-137 (2017-03-04)
Treatment with beta-blockers appears to show inferior reduction in central versus peripheral blood pressure. We aimed to examine simultaneous changes in central and peripheral blood pressure, vascular resistance, cardiac function and arterial stiffness during beta-blockade. Haemodynamics were investigated after 3
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