32138

Doripenem monohydrate

VETRANAL^®, analytical standard

• Sinónimos: (4R,5S,6S)-6-[(1R)-1-Hydroxyethyl]-4-methyl-7-oxo-3-[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• Fórmula empírica (notación de Hill): C₁₅H₂₄N₄O₆S₂ · H₂O
• Número de CAS: 364622-82-2
• Peso molecular: 438.52
• Beilstein/REAXYS Number: 15340136
• MDL number: MFCD09749887
• UNSPSC Code: 41116107
• PubChem Substance ID: 329754061
• NACRES: NA.24

Propiedades

• grade: analytical standard
• Quality Level: 100
• product line: VETRANAL^®
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): forensics and toxicology; veterinary
• format: neat
• storage temp.: 2-8°C
• SMILES string: [H]O[H].NS(NC[C@H](C1)NC[C@H]1SC2=C(C(O)=O)N3C([C@]([H])([C@H](O)C)[C@@]3([H])[C@H]2C)=O)(=O)=O
• InChI: 1S/C15H24N4O6S2.H2O/c1-6-11-10(7(2)20)14(21)19(11)12(15(22)23)13(6)26-9-3-8(17-5-9)4-18-27(16,24)25;/h6-11,17-18,20H,3-5H2,1-2H3,(H,22,23)(H2,16,24,25);1H2/t6-,7-,8+,9+,10-,11-;/m1./s1
• InChI key: NTUBEBXBDGKBTJ-WGLOMNHJSA-N

Descripción

General description

Doripenem belongs to the carbapenems family of β-lactam antibiotic compounds.

Application

Doripenem monohydrate can be used as the precursor for the preparation of doripenem which may be used as an analytical reference standard for the determination of doripenem in:

• Bovine muscle by liquid chromatography combined with tandem mass spectrometry (LC-MS/MS).
• Bulk drug and formulations by high performance thin layer chromatography (HPTLC).
• Medicinal products by capillary electrophoresis coupled to ultraviolet (UV) detector as well as micellar electrokinetic chromatography (MEKC) with UV detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable