03641

Cloruro de dansilo

for HPLC derivatization, LiChropur^™, ≥99.0% (HPLC)

• Sinónimos: Cloruro de 5-(dimetilamino)naftaleno-1-sulfonilo, DNSCl
• Fórmula empírica (notación de Hill): C₁₂H₁₂ClNO₂S
• Número de CAS: 605-65-2
• Peso molecular: 269.75
• Beilstein/REAXYS Number: 2217205
• EC Number: 210-092-6
• MDL number: MFCD00003985
• UNSPSC Code: 41116105
• PubChem Substance ID: 329747747
• NACRES: NA.22

Propiedades

• grade: for HPLC derivatization
• Quality Level: 100
• assay: ≥99.0% (HPLC)
• form: powder or crystals
• quality: LiChropur^™
• technique(s): HPLC: suitable
• mp: 72-74 °C (lit.)
• solubility: acetone: 0.2 g/10 mL, clear to slightly turbid, yellow to very dark yellow-orange
• storage temp.: 2-8°C
• SMILES string: CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O
• InChI: 1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3
• InChI key: XPDXVDYUQZHFPV-UHFFFAOYSA-N

Descripción

General description

Dansyl chloride is a fluorogenic reagent which is typically employed for the derivatization of amino acids.

Application

Dansyl chloride has been used for the fluorogenic labeling of xenoestrogens, 4-nonylphenol and bisphenol A prior to their determination by high-performance liquid chromatography (HPLC) with fluorescence detection. It has also been used for the derivatization of icariin in human serum samples after oral administration of Epimedium decoction, followed by its determination using ultrasensitive LC-tandem mass spectrometry (LC-MS) and for the derivatization of antitumoral agent ES-285 in dog plasma followed by its analysis by HPLC equipped with ultraviolet and fluorescence detection.

Reactivo fluorógeno para la derivatización N-terminal fluorescente de aminoácidos y péptidos y para la detección mediante HPLC de fase inversa.

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Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• pictograms: GHS05
• signalword: Danger
• hcodes: H290,H314
• pcodes: P234 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3