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Merck
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Key Documents

MAB4337

Sigma-Aldrich

Anti-UTF-1 Antibody, clone 5G10.2

clone 5G10.2, Chemicon®, from mouse

Sinónimos:

Anti-AI505934

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

5G10.2, monoclonal

species reactivity

mouse, human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunocytochemistry: suitable
western blot: suitable

input

sample type induced pluripotent stem cell(s)
sample type: mouse embryonic stem cell(s)
sample type: human embryonic stem cell(s)

isotype

IgG1κ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... UTF1(8433)

General description

UTF1 is a transcription factor that was originally identified due to its expression in Embryonic Stem (ES) cells, Embryonic Carcinoma (EC) cells, and germ line tissues. Expression was not found in adult tissues. It was thought at the time that UTF1 might play an important role in early molecular events of embryogenesis. Subsequent studies have shown that UTF1 is a target of the Oct-4 / Sox-2 complex, a key determinant of pluripotency in stem cells

Immunogen

Recombinant GST Fusion protein, human UTF-1

Application

Anti-UTF-1 Antibody, clone 5G10.2 detects level of UTF-1 & has been published & validated for use in ELISA, WB & IC.

Physical form

Format: Purified

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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K von Kopylow et al.
Molecular human reproduction, 22(4), 229-239 (2016-01-23)
It is possible to isolate pure populations of single potential human spermatogonial stem cells without somatic contamination for down-stream applications, for example cell culture and gene expression analysis. We isolated pure populations of single potential human spermatogonial stem cells (hSSC)
Takashi Nagai et al.
Journal of medical case reports, 14(1), 233-233 (2020-12-02)
Transverse testicular ectopia (TTE) is a rare anomaly in which both testes descend through a single inguinal canal into the same hemiscrotum. Although almost 20-50% of patients with TTE exhibit persistent Müllerian duct syndrome (PMDS) and many genetic analyses have
Christopher W Genheimer
Methods in molecular biology (Clifton, N.J.), 1001, 341-351 (2013-03-16)
Determining the in vivo response to cellular therapies is important in evaluating the effectiveness of regenerative medicine therapies. Such treatment modalities leverage the treated individual's ability to elicit the body's innate healing response to repair/regenerate damaged tissues or organs. Detailed
Xiao-Ling Wu et al.
Carcinogenesis, 34(7), 1660-1668 (2013-03-29)
Undifferentiated embryonic cell transcription factor-1 (UTF1) is an important transcription factor during development, which plays critical roles in cell fate determination. However, its expression and function in somatic tissues remain unclear. Here, we investigated the expression pattern of the UTF1
A L Caldeira-Brant et al.
Reproduction (Cambridge, England), 159(4), 437-451 (2020-01-29)
Human spermatogonial stem cells (SSCs) are an essential source to maintain spermatogenesis as an efficient process for daily sperm production with high self-renewal capacity along adulthood. However, the phenotype and the subpopulation that represent the real reserve SSC for the

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