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Key Documents

AB5482

Sigma-Aldrich

Anti-Superoxide Dismutase 1 Antibody

serum, Chemicon®

Sinónimos:

SOD1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, mouse

should not react with

human

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SOD1(6647)

General description

Mutations in the copper/ zinc superoxide dismutase (SOD1) gene are associated with 15- 20% of the familial forms of motoneuron disease. This 153 amino acid metalloenzyme is expressed in virtually all cells of all organisms above bacteria and is highly conserved across species, although some minor variations do occur. The incorporation of the mutated form of the SOD1 human gene into a transgenic mouse leads to the onset of the disease that closely resembles the human condition. These animals become weak at about 2-4 months of age and rapidly lose function, which results in death 4- 6 weeks later.

Specificity

Superoxide Dismutase 1 (SOD1), mouse and rat specific. No reactivity with human SOD1

Immunogen

Synthetic peptide corresponding to amino acids 25-37 of mouse SOD1.

Application

Detect Superoxide Dismutase 1 using this Anti-Superoxide Dismutase 1 Antibody validated for use in WB.
Research Category
Neuroscience
Research Sub Category
Oxidative Stress
Western blotting: 1:200-1:500 (see images)

Optimal working dilutions must be determined by end user.

Physical form

Rabbit serum. Lyophilized. Contains no preservative. Reconstitute with 50 μL of sterile water.

Storage and Stability

Maintain lyophilized material at -70°C (dry) for up to 12 months after date of receipt. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1) can be added for additional stability.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

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Carrasco, DI; Bichler, EK; Seburn, KL; Pinter, MJ
Testing null
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