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Documentos clave

8.07491

Sigma-Aldrich

Poli(etilenglicol)

6000, for synthesis

Sinónimos:

PEG

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About This Item

Fórmula lineal:
H(OCH2CH2)nOH
Número de CAS:
Número MDL:
Código UNSPSC:
13111021
Número índice de la CE:
500-038-2
NACRES:
NA.22
En este momento no podemos mostrarle ni los precios ni la disponibilidad

presión de vapor

<0.01 hPa ( 20 °C)

Nivel de calidad

Formulario

solid

temp. de autoignición

420 °C

potencia

28000 mg/kg LD50, oral (Rat)
>20000 mg/kg LD50, skin (Rabbit)

pH

5-7 (20 °C, 100 g/L in H2O)

mp

58-63 °C

temperatura de transición

flash point 270 °C

densidad

1.2 g/cm3 at 20 °C

temp. de almacenamiento

2-30°C

cadena SMILES

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Clave InChI

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Descripción general

Polyethylene glycol (PEG) is a synthetic, hydrophilic, biocompatible polymer that has a wide range of uses in PEGylation, surface conjugation, nanoparticle coating, and crosslinking for hydrogels, etc. PEGs are made by polymerizing ethylene oxide via a ring-opening reaction to produce a wide range of molecular weights and molecular weight distributions (polydispersity).

Aplicación

Polyethylene glycol 6000 is a non-ionic surfactant that can be used as a structure-directing agent to prepare mesoporous γ-Al2O3. PEG 6000 induced the formation of the lamellate structure morphology of boehmite nanoparticles with improved textural properties such as high surface area, larger pore volume, and pore size.[1] It is also used in drug formulations to enhance the dissolution rate of the poorly water-soluble drug molecule.[2][3] PEG-6000 can also be used in the purification of nucleic acids via the selective precipitation method. This approach is economically cost-effective and faster than the commonly employed chromatographic purification method.[4]

Nota de análisis

Melting range (lower value): ≥ 59 °C
Melting range (upper value): ≤ 64 °C
Hydroxyl value: 16 - 23
Average molecular mass: 5000 - 7000
Identity (IR): passes test

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

281.5 °F - closed cup

Punto de inflamabilidad (°C)

138.6 °C - closed cup


Certificados de análisis (COA)

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S Biswal et al.
AAPS PharmSciTech, 9(2), 563-570 (2008-05-07)
The aim of the present study was to enhance the dissolution rate of gliclazide using its solid dispersions (SDs) with polyethylene glycol (PEG) 6000. The phase solubility behavior of gliclazide in presence of various concentrations of PEG 6000 in 0.1
S Verheyen et al.
International journal of pharmaceutics, 249(1-2), 45-58 (2002-11-16)
Solid dispersion literature, describing the mechanism of dissolution of drug-polyethylene glycol dispersions, still shows some gaps; (A). only few studies include experiments evaluating solid solution formation and the particle size of the drug in the dispersion particles, two factors that
A facile rout to synthesis lamellate structure mesoporous alumina using polyethylene glycol 6000 (PEG, molecular weight= 6000) as structure directing agent
Su Ai-ping, et al.
Microporous and Mesoporous Materials : The Official Journal of the International Zeolite Association, 159, 36-41 (2012)
Purification of nucleic acids by selective precipitation with polyethylene glycol 6000.
Axel Schmitz et al.
Analytical biochemistry, 354(2), 311-313 (2006-05-27)

Questions

  1. Is it possible to use the product Polyethylene glycol 6000 (8074911000) to soften seed coats to aid in germination?

    1 answer
    1. The information from Jelitto Perennial Seeds suggests that for hard-shelled seeds, mechanical damaging of the shell or treatment with a softener such as Polyethylene glycol 6000 (PEG 6000) can be helpful for quicker swelling. However, there is no specific mention of product number 807491 in particular for this purpose.

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