662041

U-73343

A cell-permeable analog of U-73122 that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

• Sinónimos: U-73343, 1-[6-((17β-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl]-2,5-pyrrolidinedione
• Fórmula empírica (notación de Hill): C₂₉H₄₂N₂O₃
• Número de CAS: 142878-12-4
• Peso molecular: 466.66
• MDL number: MFCD00211221
• UNSPSC Code: 51111800
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: off-white
• solubility: ethanol: 1 mg/mL; DMSO: 2 mg/mL; chloroform: 200 mg/mL
• shipped in: ambient
• storage temp.: 10-30°C
• InChI: 1S/C29H42N2O3/c1-29-16-15-23-22-10-8-21(34-2)19-20(22)7-9-24(23)25(29)11-12-26(29)30-17-5-3-4-6-18-31-27(32)13-14-28(31)33/h8,10,19,23-26,30H,3-7,9,11-18H2,1-2H3/t23-,24-,25+,26+,29+/m1/s1
• InChI key: CJHWFIUASFBCKN-ZRJUGLEFSA-N

Descripción

General description

A cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

A cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
Negative control of U-73122 in the inhibition of phospholipase C

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Irritant (B)

Reconstitution

For storage in chloroform, aliquot into single use volumes, evaporate to dryness under a stream of nitrogen and freeze (-20°C). DMSO stocks solutions are stable for up to 6 months at -20°C.

Other Notes

Tatrai, A., et al. 1994. Biochim. Biophys. Acta 1224, 595.
Bleasdale, J.E., et al. 1990. J. Pharmacol. Exp. Ther.255, 756.
Smith, R.J., et al. 1990. J. Pharmacol. Exp. Ther.253, 688.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable