341482

Ferritin, Human Liver

Ferritin, Human Liver, CAS 9007-73-2, is a native, sterile-filtered ferritin that is suitable for use in immunoassays, as an immunogen, and in enzyme/radiolabeling.

• Sinónimos: Ferritin, Human Liver
• Número de CAS: 9007-73-2
• Número MDL: MFCD00081593
• Código UNSPSC: 12352202
• NACRES: NA.77

Propiedades

• origen biológico: human
• Nivel de calidad: 100
• descripción: RTECS - LK0500000
• Ensayo: ≥95% (SDS-PAGE)
• Formulario: liquid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: do not freeze
• técnicas: enzyme immunoassay: suitable
• impurezas: Antibodies to HIV1, HIV2, Hepatitis B, Hepatitis C, tested negative (by certified tests)
• solubilidad: water: soluble
• idoneidad: suitable for immunoassay
• Nº de acceso Protein ID: AAA35832.1
• Nº de acceso UniProt: P02792; P02794
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• Información sobre el gen: human ... FTH1(2495) , FTL(2512)

Descripción

Descripción general

Research area: Cell signaling

Ferritin is a major iron storage protein. It exists in a two functionally and genetically different subunits namely, the acidic, heavy or H-chain and the basic, light or L-chain. Native ferritin from human liver. Sterile-filtered.

Aplicación

Ferritin is suitable for use in immunofluorescence assay, immunoassays, as an immunogen, and in enzyme/radiolabeling.

Acciones bioquímicas o fisiológicas

Ferritin is a crucial protein that has multiple functions in iron metabolism and immune regulation. It helps in maintaining the iron balance. H-ferritin is involved in various processes such as regulating immune function, hematopoiesis, hepatocyte apoptosis, and cell differentiation. Additionally, ferritin can act as a proinflammatory cytokine through protein kinase C-zeta (PKC-ζ) and nuclear factor kappa B (NFκB) signaling pathways in certain cells.(1) Ferritin serves as both an immune-suppressor and a signaling molecule, contributing to the regulation of lymphoid and myeloid cell proliferation.

Envase

Please refer to vial label for lot-specific concentration.

Advertencia

Toxicity: Standard Handling (A)

Forma física

In 0.9% NaCl, 0.1% NaN₃, pH 7.0.

Otras notas

Addison, J.M., et al. 1983. FEBS Lett.164, 139.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable