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Merck
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Documentos clave

05-753

Sigma-Aldrich

Anti-WT1 Antibody, clone 6F-H2

clone 6F-H2, Upstate®, from mouse

Sinónimos:

Anti-AWT1, Anti-GUD, Anti-NPHS4, Anti-WAGR, Anti-WIT-2, Anti-WT-1, Anti-WT33

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

forma del anticuerpo

purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

6F-H2, monoclonal

reactividad de especies

human

fabricante / nombre comercial

Upstate®

técnicas

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

isotipo

IgG1

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... WT1(7490)

Especificidad

WT1

Inmunógeno

6His-tagged fusion protein corresponding to residues 1-181 of human WT1 (Wilms tumor)

Aplicación

Anti-WT1 Antibody, clone 6F-H2 is a Mouse Monoclonal Antibody for detection of WT1 also known as Wilms′ Tumor & has been tested in WB, ICC & IHC.

Calidad

routinely evaluated by immunoblot on RIPA lysates from Jurkat and Raji cells

Descripción de destino

55-60kDa

Forma física

Format: Purified

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Opcional

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1


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Toru Sakairi et al.
American journal of physiology. Renal physiology, 298(3), F557-F567 (2009-12-04)
Evidence suggests that loss of podocytes into urine contributes to development of glomerular diseases; shed podocytes are frequently viable and proliferate in culture conditions. To determine the phenotypic characteristics of viable urinary cells derived from human subjects, we established long-term
Zenglai Tan et al.
Scientific reports, 8(1), 16618-16618 (2018-11-11)
The kidney is a complex organ that is comprised of thousands of nephrons developing through reciprocal inductive interactions between metanephric mesenchyme (MM) and ureteric bud (UB). The MM undergoes mesenchymal to epithelial transition (MET) in response to the signaling from
Caihua Xu et al.
PloS one, 8(8), e68837-e68837 (2013-08-13)
The Wilms' tumor suppressor gene (WT1) has been identified as an oncogene in many malignant diseases such as leukaemia, breast cancer, mesothelioma and lung cancer. However, the role of WT1 in non-small-cell lung cancer (NSCLC) carcinogenesis remains unclear. In this
Kazunori Inoue et al.
The Journal of clinical investigation, 129(3), 1295-1313 (2019-02-19)
We identified 2 genes, histone deacetylase 1 (HDAC1) and HDAC2, contributing to the pathogenesis of proteinuric kidney diseases, the leading cause of end-stage kidney disease. mRNA expression profiling from proteinuric mouse glomeruli was linked to Connectivity Map databases, identifying HDAC1
Chen Wu et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 8(9), 1163-1169 (2013-08-16)
The Wilms' tumor gene (WT1) has been identified as an oncogene in many malignant diseases, and aberrant WT1 expression has been linked to development, progression, and prognosis of non-small-cell lung cancer (NSCLC). We sought to investigate the underlying mechanism of

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