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Key Documents

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H6377

Sigma-Aldrich

1-Hydroxypyridine-2-thione zinc salt

≥95%

Sinónimos:

Mercaptopyridine N-oxide zinc salt, Pyrithione

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About This Item

Fórmula empírica (notación de Hill):
C10H8N2O2S2Zn
Número de CAS:
13463-41-7
Peso molecular:
317.70
EC Number:
236-671-3
MDL number:
MFCD00067336
UNSPSC Code:
12352100
PubChem Substance ID:
57654263
NACRES:
NA.22

Quality Level

100

assay

≥95%

SMILES string

O1N2C=CC=CC2=[S][Zn]13ON4C=CC=CC4=[S]3

InChI

1S/2C5H5NOS.Zn/c2*7-6-4-2-1-3-5(6)8;/h2*1-4,8H;/q;;+2/p-2

InChI key

OTPSWLRZXRHDNX-UHFFFAOYSA-L

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Application


  • Antimicrobial nanocoatings: The compound 1-Hydroxypyridine-2-thione zinc salt was evaluated for its efficacy in antimicrobial nanocoatings, showcasing its role in enhancing the performance of such coatings used in healthcare and industrial environments to prevent microbial contamination (Molling et al., 2014).

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 1B - STOT RE 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number
MKCW9769
MKCT8891
MKCQ6554
MKCL4181
SLBL1836V

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J R Schwartz et al.
The British journal of dermatology, 165 Suppl 2, 18-23 (2011-09-23)
Pathogenesis of dandruff/seborrhoeic dermatitis (D/SD) involves Malassezia yeasts, leading to the most widely accepted treatment strategy of topical application of antifungal agents, usually from rinse-off shampoos. The scalp spatial distribution of Malassezia must be mirrored by the distribution of the
K J Mills et al.
The British journal of dermatology, 166 Suppl 2, 33-40 (2012-06-15)
Dandruff/seborrhoeic dermatitis is a common scalp condition that is characterized by flakes, pruritus and sometimes mild erythema. These symptoms reflect tissue level events that are poorly understood at the molecular level. The purpose of this work was: (i) to compare
M Tailler et al.
Oncogene, 31(30), 3536-3546 (2011-11-23)
Despite recent progress in the treatment of acute myeloid leukemia (AML), the prognosis of this rather heterogeneous disease remains poor and novel chemotherapeutics that specifically target leukemic cells must be developed. To address this need at the preclinical level, we
Tomohiro M Oyama et al.
Chemosphere, 87(11), 1316-1322 (2012-02-24)
Zinc pyrithione is used as an antifouling agent. However, the environmental impacts of zinc pyrithione have recently been of concern. Zinc induces diverse actions during oxidative stress; therefore, we examined the effect of zinc pyrithione on rat thymocytes suffering from
Nancy L Reeder et al.
Antimicrobial agents and chemotherapy, 55(12), 5753-5760 (2011-09-29)
Zinc pyrithione (ZPT) is an antimicrobial material with widespread use in antidandruff shampoos and antifouling paints. Despite decades of commercial use, there is little understanding of its antimicrobial mechanism of action. We used a combination of genome-wide approaches (yeast deletion
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