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717142

Sigma-Aldrich

Poly(ethylene glycol) dithiol

average Mn 1,000, thiol

Sinónimos:

Polyethylene glycol, PEG dithiol

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About This Item

Fórmula lineal:
HSCH2CH2(OCH2CH2)nSH
UNSPSC Code:
12162002
NACRES:
NA.23

product name

Poly(ethylene glycol) dithiol, average Mn 1,000

form

solid

Quality Level

100

mol wt

average Mn 1,000

reaction suitability

reagent type: cross-linking reagent
reactivity: thiol reactive

mp

29-33 °C

Ω-end

thiol

α-end

thiol

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

2-8°C

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Application

Thiol functionalized nanoparticles may be used in mucoadhesive drug delivery, synthesis of dithiol terminated amphiphilic diblock copolymer, Bidentate dithiol-poly(ethylene glycol)-poly(d,l-lactide) (SH2-PEG-PDLLA). Gold nanoparticles may be easily functionalized with PEG dithiols by simple ligand exchange.

Other Notes

Molecular weight: Mn 900-1,100

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
MKCW4873
MKCR7598
MKCQ0755
MKCH8048
MKCG7818

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Jian Yang et al.
Biomacromolecules, 15(4), 1346-1354 (2014-03-13)
Thiol-modified nanoparticles have potential applications in mucoadhesive drug delivery and have been examined in this regard for topical ocular delivery. In this paper we provide a simple method for the synthesis of a dithiol terminated amphiphilic diblock copolymer. Bidentate dithiol-poly(ethylene
Nadeau J
Introduction to Experimental Biophysics: Biological Methods for Physical Scientists null
Qiang Wei et al.
ACS biomaterials science & engineering, 6(8), 4687-4701 (2021-01-19)
Hydrogels have been widely explored for the delivery of cells in a variety of regenerative medicine applications due to their ability to mimic both the biochemical and physical cues of cell microniches. For bone regeneration, in particular, stiff hydrogels mimicking

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