Saltar al contenido
Merck
Todas las fotos(1)

Key Documents

View All Documentation

702153

Sigma-Aldrich

Hydroxyapatite

nanoparticles, dispersion, 10 wt. % in H2O, <200 nm particle size (BET)

Sinónimos:

Calcium hydroxide phosphate, Calcium hydroxylapatite, Calcium hydroxyphosphate, Nano hydroxyapatatite, Pentacalcium hydroxide triphosphate

Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
Todas las fotos(1)

About This Item

Fórmula lineal:
[Ca5(OH)(PO4)3]x
Número de CAS:
12167-74-7
Peso molecular:
502.31
MDL number:
MFCD00010904
UNSPSC Code:
12352302
PubChem Substance ID:
329762350
NACRES:
NA.23

form

dispersion
nanoparticles

Quality Level

100

contains

≤0.025 wt. % dispersant (non-metal based)

concentration

10 wt. % in H2O

surface area

14.3 m2/g , typical

particle size

<200 nm (BET)

pH

4-6

density

1.038 g/mL at 25 °C

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

¿Está buscando productos similares? Visita Guía de comparación de productos

General description

Hydroxyapatite(HAP) is an osteoconductive bioceramic material which has uniqueability to form direct bonds with living tissues. It can be easily prepared byvarious techniques such as sol-gel, hydrothermal, multiple emulsion, biomimeticdeposition, and electrodeposition.

Application

Hydroxyapatite can be used as:
  • An implant material for bone substitute due to its chemical similarity to the inorganic component of bone and osteo inductive properties.
  • A vehicle for gene and drug delivery because of its encapsulation capacity and affinity to several drugs and proteins.
  • A pH responsive particulate emulsifier.

Features and Benefits

  • Biocompatible
  • Osteoconductive
  • Stable under physiological conditions
  • High mechanical strength

Legal Information

Product of Engi-Mat Co.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number
MKCQ7691
MKCS4260
MKCP8250
MKCN6392
MKCL6094

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

Busque por un COA

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Martin P Reichhardt et al.
Life science alliance, 3(4) (2020-02-27)
The scavenger receptor cysteine-rich (SRCR) family of proteins comprises more than 20 membrane-associated and secreted molecules. Characterised by the presence of one or more copies of the ∼110 amino-acid SRCR domain, this class of proteins have widespread functions as antimicrobial
Xi Chen et al.
The Journal of biological chemistry, 289(16), 11162-11174 (2014-03-13)
Calcium phosphate precipitates (CPPs) form complexes with DNA, which enter cells via endocytosis. Under this condition CPPs induce autophagy via the canonic autophagy machinery. Here we showed that CPP-induced autophagy was also dependent on endocytosis as the process was significantly
Thomas Lyon et al.
The Journal of bone and joint surgery. American volume, 95(23), 2088-2096 (2013-12-07)
Recombinant human bone morphogenetic protein-2 (rhBMP-2) applied on an absorbable collagen sponge improves open tibial fracture-healing as an adjunct to unreamed intramedullary nail fixation. We evaluated rhBMP-2 and a new, injectable calcium phosphate matrix (CPM) formulation in acute closed tibial
Tie Liu et al.
Bone, 56(1), 110-118 (2013-06-05)
As an alternative to an autologous bone graft, deproteinized bovine bone (DBB) is widely used in the clinical dentistry. Although DBB provides an osteoconductive scaffold, it is not capable of enhancing bone regeneration because it is not osteoinductive. In order
Ehud Segal et al.
PloS one, 4(4), e5233-e5233 (2009-04-22)
There is an immense clinical need for novel therapeutics for the treatment of angiogenesis-dependent calcified neoplasms such as osteosarcomas and bone metastases. We developed a new therapeutic strategy to target bone metastases and calcified neoplasms using combined polymer-bound angiogenesis inhibitors.
Ver todos los artículos relacionados

Artículos

Nanomaterials for Biomedical Applications

Nanoparticles can be used for applications such as growing cells for tissue engineering, nanocomposites used in orthopedics, and miniaturized sensors for DNA, pathogens, and chemicals.

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

Póngase en contacto con el Servicio técnico