586846
N-Benzoyladenosine
96%
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About This Item
Fórmula empírica (notación de Hill):
C17H17N5O5
Número de CAS:
Peso molecular:
371.35
Beilstein/REAXYS Number:
632501
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22
Productos recomendados
Quality Level
assay
96%
form
solid
optical activity
[α]20/D -49°, c = 1% in DMSO
mp
141-145 °C (lit.)
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NC(=O)c4ccccc4)ncnc23
InChI
1S/C17H17N5O5/c23-6-10-12(24)13(25)17(27-10)22-8-20-11-14(18-7-19-15(11)22)21-16(26)9-4-2-1-3-5-9/h1-5,7-8,10,12-13,17,23-25H,6H2,(H,18,19,21,26)/t10-,12-,13-,17-/m1/s1
InChI key
NZDWTKFDAUOODA-CNEMSGBDSA-N
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Exchange protein activated by cAMP (Epac-1) is an important signaling mechanism for cAMP-mediated effects, yet factors that change Epac-1 levels are unknown. Such factors are relevant because it has been postulated that Epac-1 directly affects fibrogenesis. Prostaglandin E
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cAMP has been shown to inhibit vascular smooth muscle cell proliferation and exerts a vasculoprotective effect. An upregulation of the early growth response protein-1 (Egr-1) expression has been linked with the development of atherosclerosis and intimal hyperplasia. We have recently
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