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535311

Sigma-Aldrich

Poly(N-isopropylacrylamide)

Mn ~40,000

Sinónimos:

NIPAM polymer, PNIPAM, Polyacrylamide, polyNIPAM

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About This Item

Fórmula lineal:
CH3(C6H11NO)nCH3
Número de CAS:
25189-55-3
Número MDL:
MFCD00284282
Código UNSPSC:
12162002
ID de la sustancia en PubChem:
24877546
NACRES:
NA.23

mol peso

Mn 20,000-60,000
Mn ~40,000

Nivel de calidad

100

mp

96 °C

cadena SMILES

CC(C)NC(=O)C=C

InChI

1S/C6H11NO/c1-3-5-7-6(8)4-2/h4H,2-3,5H2,1H3,(H,7,8)

Clave InChI

WDFKEEALECCKTJ-UHFFFAOYSA-N

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Categorías relacionadas

Aplicación

PNIPAM-based Smart Surfaces for Cell Sheet Tissue Engineering
Thermosensitive polymer, can be used to form a hydrogel. Aqueous polymer solution undergoes a phase transition from a soluble to an insoluble state when the temperature is raised to ca. 32 °C.

Forma física

Thermosensitive polymer, hydrogel

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
MKCV7874
MKCR8778
MKCR4152
MKCM8563
MKCM8561

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Poly(N-isopropyl acrylamide) NHS ester end functionalized, average Mn 5,000

Sigma-Aldrich

900188

Poly(N-isopropyl acrylamide)

N-Isopropylmethacrylamide 97%

Sigma-Aldrich

423548

N-Isopropylmethacrylamide

Albert J de Graaf et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(3), 582-590 (2012-09-14)
In this paper it is shown that when a thermosensitive hydrogel based on poly(N-isopropylacrylamide)-poly(ethylene glycol)-poly(N-isopropylacrylamide) (pNIPAm-PEG-pNIPAm) was transferred into water, flower-like micelles were continuously released as long as the medium was regularly refreshed. On the other hand, if the medium
Yan Xia et al.
Chemical communications (Cambridge, England), 49(25), 2566-2568 (2013-02-21)
Site-specific protein conjugates with RAFT polymers were synthesized using expressed protein ligation. Stable micelles were formed from both linear block copolymer and Y-shaped conjugates.
Kornelia Gawlitza et al.
Physical chemistry chemical physics : PCCP, 14(27), 9594-9600 (2012-06-12)
The aim of the present work is the use of a water soluble enzyme in an organic solvent, still with a pronounced catalytic activity. Therefore, lipase B from Candida antarctica (CalB) is immobilized within micron-sized thermosensitive p-NIPAM hydrogel particles using
Guiying Li et al.
International journal of biological macromolecules, 50(4), 899-904 (2012-06-09)
Thermo-sensitive poly(N-isopropyl acrylamide-co-vinyl pyrrolidone)/chitosan [P(NIPAM-co-NVP)/CS] semi-IPN hydrogels with improved loading capacity and sustained release for anionic drugs NAP were prepared by free-radical polymerization. The LCST of hydrogels was adjusted to the vicinity of body temperature by introducing hydrophilic NVP. The
Pengju Pan et al.
Langmuir : the ACS journal of surfaces and colloids, 28(40), 14347-14356 (2012-09-28)
Linear and miktoarm star-shaped diblock copolymers consisting of single-stranded DNA and poly(N-isopropylacrylamide) (PNIPAAm) with various compositions were synthesized via atom transfer radical polymerization and click chemistry. The temperature-responsive phase transition behavior, micellization, was systematically examined using UV-vis spectrometry, high-sensitivity differential
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