528218

N-Chlorophthalimide

96%

• Sinónimos: 2-Chloro-1H-isoindole-1,3(2H)-dione, 2-Chloro-2,3-dihydro-1H-isoindole-1,3-dione, 2-Chloroisoindole-1,3-dione, 2-Chloroisoindoline-1,3-dione, Phthalimide chloride, Phthalimidoyl chloride
• Fórmula empírica (notación de Hill): C₈H₄ClNO₂
• Número de CAS: 3481-09-2
• Peso molecular: 181.58
• EC Number: 222-459-8
• MDL number: MFCD00023027
• UNSPSC Code: 12352100
• PubChem Substance ID: 24877568
• NACRES: NA.22

Propiedades

• Quality Level: 100
• assay: 96%
• mp: 188-198 °C (lit.)
• functional group: imide
• SMILES string: ClN1C(=O)c2ccccc2C1=O
• InChI: 1S/C8H4ClNO2/c9-10-7(11)5-3-1-2-4-6(5)8(10)12/h1-4H
• InChI key: WDRFYIPWHMGQPN-UHFFFAOYSA-N

Descripción

General description

N-Chlorophthalimide in anhydrous acetic acid serves as a useful oxidizing reagent for use in various direct titrimetric analyses. N-Chlorophthalimide can be synthesized by reacting phthalimide, t-butyl hypochlorite, water and t-butyl alcohol. It participates in the synthesis of 2-amino-3-benzoyl-α-(methylthio)phenylacetamide.

Application

N-Chlorophthalimide may be employed in the synthesis of:

• α-amino acetal
• α-amino nitro compounds
• vicinal diamine
• α,β-unsaturated vicinal haloamino nitro compound

It may also be used as a chlorination reagent for the synthesis of 3-(methylthio)oxindoles.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves