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487090

Sigma-Aldrich

Agua-18O

99 atom % 18O

Sinónimos:

18O Labeled water

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About This Item

Fórmula lineal:
H218O
Número de CAS:
14314-42-2
Peso molecular:
20.02
MDL number:
MFCD00064503
UNSPSC Code:
12142200
PubChem Substance ID:
24872241
NACRES:
NA.12

description

Normalized with respect to hydrogen

Quality Level

200

isotopic purity

99 atom % 18O

bp

100 °C (lit.)

mp

0 °C (lit.)

density

1.11 g/mL at 20 °C (lit.)

mass shift

M+2

SMILES string

[18OH2]

InChI

1S/H2O/h1H2/i1+2

InChI key

XLYOFNOQVPJJNP-NJFSPNSNSA-N

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General description

H2180 is isotopically modified compound consisting of two hydrogen atoms covalently bonded to oxygen-18. It is most convenient to store, transport and use Oxygen-18 in the form of water enriched with this isotope.

Application

O-18 enriched water is used in Positron-Emission Tomography (PET), a nuclear imaging technique that is used to observe metabolic processes in the body as an aid to the diagnosis of disease such as tumors, staging of cancer, metastasis, dementia, etc. H2180 is currently the only potential universal bacterial substrate suitable for stable isotope probing (SIP). It has been used in the quantification of population-specific growth dynamics in benthic bacterial communities in response to changing redox conditions.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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H H Coenen et al.
Nuclear medicine and biology, 37(7), 727-740 (2010-09-28)
Positron emission tomography (PET) is a rapidly expanding clinical modality worldwide thanks to the availability of compact medical cyclotrons and automated chemistry for the production of radiopharmaceuticals. There is an armamentarium of fluorine-18 ((18)F) tracers that can be used for
Elizabeth A Rettedal et al.
MicrobiologyOpen, 4(2), 208-219 (2015-02-05)
Current limitations in culture-based methods have lead to a reliance on culture-independent approaches, based principally on the comparative analysis of primary semantides such as ribosomal gene sequences. DNA can be remarkably stable in some environments, so its presence does not
Ömer K Coskun et al.
The ISME journal, 13(6), 1546-1559 (2019-02-21)
The benthos in estuarine environments often experiences periods of regularly occurring hypoxic and anoxic conditions, dramatically impacting biogeochemical cycles. How oxygen depletion affects the growth of specific uncultivated microbial populations within these diverse benthic communities, however, remains poorly understood. Here

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