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Merck

204625

Sigma-Aldrich

Thallium(I) sulfate

99.99% trace metals basis

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About This Item

Fórmula lineal:
Tl2SO4
Número de CAS:
Peso molecular:
504.83
EC Number:
MDL number:
UNSPSC Code:
12161600
eCl@ss:
38120904
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

99.99% trace metals basis

form

solid

reaction suitability

core: thallium
reagent type: catalyst

mp

632 °C (lit.)

density

6.77 g/mL at 25 °C (lit.)

SMILES string

[Tl+].[Tl+].[O-]S([O-])(=O)=O

InChI

1S/H2O4S.2Tl/c1-5(2,3)4;;/h(H2,1,2,3,4);;/q;2*+1/p-2

InChI key

YTQVHRVITVLIRD-UHFFFAOYSA-L

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General description

Thallium(I) sulfate is mainly used in organic synthesis as an oxidizing agent. It can facilitate the oxidation of various organic compounds, such as alcohols, to corresponding aldehydes or ketones. This reaction is commonly known as the Reformatsky reaction.1 Additionally, thallium sulfate is employed in the preparation of thallium salts for use in analytical chemistry and research applications. It is also utilized in the production of luminous paints, photoelectric cells, and low-melting glasses.

Application

Thallium(I)sulfate is also utilized in:

  • the synthesis of alkylated cyclopentadienes and 7-substitutedbicyclo[2.2.1]heptane derivatives
  • inthe preparation of thallium borate species such as TlBPH43

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 2 - Skin Irrit. 2 - STOT RE 1 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Methoxymethylation of thallous cyclopentadienide. Simplified preparation of a key intermediate for the synthesis of prostaglandins
Elias J. Corey, Urs Koelliker, and Jorg Neuffer
Journal of the American Chemical Society, 93(6), 1489?1490-1489?1490 (1971)
Altered testicular enzyme patterns in rats after long-term exposure to thallium sulphate.
C Gregotti et al.
Journal de toxicologie clinique et experimentale, 5(4), 265-271 (1985-07-01)
D B Peele et al.
Neurobehavioral toxicology and teratology, 8(3), 273-277 (1986-05-01)
Flavor aversions induced by intraperitoneal (IP) and oral (PO) administration of thallium sulfate were compared in a repeated trial, two-bottle preference test. Male Long-Evans rats (N = 6/group) were given 30-min access to a 0.1% saccharin solution followed 20-min later
D Appenroth et al.
Toxicology, 96(3), 203-215 (1995-02-27)
Until now the effect of thallium (Tl) on renal function has not been investigated systematically. Therefore, the dose (5, 10, 15, 20 mg Tl2SO4/kg body wt., intraperitoneally) and time-dependence of renal damage was investigated in diuresis experiments on conscious rats.
Ritu Tyagi et al.
Journal of applied toxicology : JAT, 31(7), 663-670 (2011-01-11)
Thallium (Tl) is a toxic heavy metal and its exposure to the human body causes physiological and biochemical changes due to its interference with potassium-dependent biological reactions. A high-resolution (1)H NMR spectroscopy based metabonomic approach has been applied for investigating

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