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17343

Sigma-Aldrich

Bromhexine hydrochloride

≥98.0% (AT)

Sinónimos:

2-Amino-3,5-dibromo-N-cyclohexyl-N-methylbenzylamine hydrochloride, N-(2-Amino-3,5-dibromobenzyl)-N-methylcyclohexylamine hydrochloride, Bromohexine hydrochloride

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About This Item

Fórmula empírica (notación de Hill):
C14H20Br2N2 · HCl
Número de CAS:
611-75-6
Peso molecular:
412.59
Beilstein/REAXYS Number:
4848376
EC Number:
210-280-8
MDL number:
MFCD00056626
UNSPSC Code:
12352100
PubChem Substance ID:
329751532
NACRES:
NA.22

assay

≥98.0% (AT)

form

powder

functional group

amine
bromo

SMILES string

Cl.CN(Cc1cc(Br)cc(Br)c1N)C2CCCCC2

InChI

1S/C14H20Br2N2.ClH/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17;/h7-8,12H,2-6,9,17H2,1H3;1H

Inchi Key

UCDKONUHZNTQPY-UHFFFAOYSA-N

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General description

Bromhexine hydrochloride is a bronchial mucolytic.

Application

Bromhexine hydrochloride was used in the secretion of pancreatic juice of low viscosity.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCBJ8156V
BCBB8827V
BCBB8827
1342515
1147328

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Tatsuhiro Tsujimoto et al.
Alcoholism, clinical and experimental research, 29(12 Suppl), 272S-276S (2005-12-31)
Abstinence is a prerequisite for the treatment of alcoholic chronic pancreatitis, but there are patients who have repeated attacks because of their inability to abstain and the consequent congestive effects of the continued alcohol intake on pancreatic juice. Bromhexine hydrochloride
Mladen Stojanov et al.
International journal of pharmaceutics, 422(1-2), 349-355 (2011-10-27)
Bromhexine hydrochloride (bromhexine) is a mucolytic agent with very low aqueous solubility. However, with addition of cyclodextrins (CD) to the formulation, this disadvantage may be limited and therapeutic doses of bromhexine in solution can be achieved. The interaction of bromhexine
Matthew E Spector et al.
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Despite better prognosis, there is a group of oropharyngeal squamous cell carcinoma (SCC) human papillomavirus (HPV)+ patients who experience treatment failure and succumb to distant metastasis. Seventy-eight previously untreated patients nested in a concurrent chemoradiation protocol were reviewed to correlate
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Saman Azodi-Deilami et al.
Applied biochemistry and biotechnology, 164(2), 133-147 (2010-11-16)
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