1370101

Lopinavir

United States Pharmacopeia (USP) Reference Standard

• Fórmula empírica (notación de Hill): C₃₇H₄₈N₄O₅
• Número de CAS: 192725-17-0
• Peso molecular: 628.80
• Número MDL: MFCD22628840
• Código UNSPSC: 41116107
• NACRES: NA.24

Propiedades

• origen biológico: synthetic
• grado: pharmaceutical primary standard
• Agency: USP/NF
• familia API: lopinavir
• Formulario: powder
• envase: pkg of 350 mg
• fabricante / nombre comercial: USP
• condiciones de almacenamiento: protect from light
• color: white to off-white
• mp: 255.2-260.6 °F (124—127°C)
• solubilidad: chloroform: soluble; isopropanol: soluble; methanol: freely soluble; methylene chloride: freely soluble; water: practically insoluble
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: N4(CCCNC4=O)[C@@H](C(C)C)C(=O)N[C@H](C[C@H](O)[C@@H](NC(=O)COc3c(cccc3C)C)Cc2ccccc2)Cc1ccccc1
• InChI: 1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1
• Clave InChI: KJHKTHWMRKYKJE-SUGCFTRWSA-N

Descripción

Descripción general

Lopinavir is an antiretroviral agent and a protease inhibitor indicated for the management of human immunodeficiency virus (HIV) infection.[1][2] It is a key component of Kaletra, the co-formulation of lopinavir and ritonavir.[3]

Aplicación

Lopinavir may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations[1][4] and plasma samples[2][3][5] by chromatography techniques.

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable