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73033AST

Supelco

Astec® CHIRALDEX™ G-TA Capillary GC Column

L × I.D. 30 m × 0.25 mm, df 0.12 μm

Sinónimos:

GC column, chiral, gamma-dextran

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About This Item

Código UNSPSC:
41115710
NACRES:
SB.54

Materiales

fused silica

descripción

GC capillary column

envase

pkg of 1 ea

Parámetros

-10-180 °C temperature (isothermal or programmed)

Valor Beta

500

df

0.12 μm

técnicas

gas chromatography (GC): suitable

L × D.I.

30 m × 0.25 mm

grupo activo de la matriz

non-bonded; 2,6-di-O-pentyl-3-trifluoroacetyl derivative of γ-cyclodextrin phase

aplicaciones

agriculture
chemicals and industrial polymers
cleaning products
clinical
cosmetics
environmental
flavors and fragrances
food and beverages
forensics and toxicology
life science and biopharma
personal care
pharmaceutical (small molecule)

tipo de columna

capillary chiral

técnica de separación

chiral

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Descripción general

Astec® CHIRALDEX G-TA is the first choice in the Group 1 CSPs (Surface Interactions, Complex Derivatives). This phase has been shown to be the most broadly-selective phase for the pharmaceutical industry, especially for the analysis of chiral intermediates and drug studies in various stages of clinical trials. Separations occur without the inclusion mechanism and are typically faster and more efficient than most chiral stationary phases. G-TA has also been used to separate parent drug enantiomers and their metabolites. G-TA has its highest selectivity for oxygen-containing analytes like alcohols, diols and polyols as the free alcohol and as an acyl derivative; amines as acyl derivatives; amino alcohols, halogens (Cl>Br>F), amino acids, hydroxy acids, lactones, furans and pyrans. It is also highly selective for halogenated compounds.

Aplicación

Astec® CHIRALDEX™ G-TA (2,6-di-O-pentyl-3-trifluoroacetyl-γ-cyclodextrin) derivatized cyclodextrin chiral stationary phase may be used in capillary gas chromatography for separation of four isomers from 7 racemic sulfinate esters. It was used in an experimental study done for cloning and characterization of three epoxide hydrolases identified by analyzing open reading frames (ORFs) of a marine bacterium, Erythrobacter litoralis HTCC2594. It was also used in HPLC and GC analyses of the conversion of epoxides during enantioselectivity of epoxide hydrolase from Agrobacterium radiobacter (EchA) using error-prone PCR and DNA shuffling.

Resistencia química o física

Temp. Limits:
  • -10 °C to 180 °C isothermal and programmed

Otras notas

We offer a variety of chromatography accessories including analytical syringes

Información legal

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIRALDEX is a trademark of Sigma-Aldrich Co. LLC

Aplicación

Referencia del producto
Descripción
Precios

G005039

GC Analysis of 2-Aminobutane (2-Butylamine) Enantiomers (N-Trifluoroacetyl Derivatives) on Astec® CHIRALDEX™ G-TA, suitable for GC

G005049

GC Analysis of 1-Methyl-3-Phenylpropylamine (4-Phenyl-2-Butylamine) Enantiomers (N-TFA Derivatives) on Astec® CHIRALDEX™ G-TA, suitable for GC

G005056

GC Analysis of β-Butyrolactone Enantiomers on Astec® CHIRALDEX™ G-TA, suitable for GC

G005061

GC Analysis of Methionine Methyl Ester Enantiomers (N-Trifluoroacetyl Derivatives) on Astec® CHIRALDEX™ G-TA, suitable for GC

G005064

GC Analysis of 2-Halohydrocarbon Enantiomers on Astec® CHIRALDEX™ G-TA, suitable for GC

G005067

GC Analysis of Mandelic Acid Methyl Ester Enantiomers on Astec® CHIRALDEX™ G-TA, suitable for GC

G005093

GC Analysis of 1,2-Alkyldiol Enantiomers (O-Trifluoroacetyl Derivatives) on Astec® CHIRALDEX™ G-TA, suitable for GC

G005122

GC Analysis of 2,5-Dimethoxytetrahydrofuran Enantiomers on Astec® CHIRALDEX™ G-TA, suitable for GC

G005096

GC Analysis of 2-Butanol Enantiomers (O-Acetyl Derivatives) on Astec® CHIRALDEX™ G-TA, suitable for GC

G005095

GC Analysis of 2-Butanol Enantiomers (O-Trifluoroacetyl Derivatives) on Astec® CHIRALDEX™ G-TA, suitable for GC

G005094

GC Analysis of 2-Butanol Enantiomers (Underivatized) on Astec® CHIRALDEX™ G-TA, suitable for GC

G005103

GC Analysis of 5-Amino-1,3,3-Trimethylcyclohexanemethylamine Enantiomers (N-TFA Derivatives) on Astec® CHIRALDEX™ G-TA, suitable for GC

G005131

GC Analysis of Glycidol Enantiomers on Astec® CHIRALDEX™ G-TA, suitable for GC

G005102

GC Analysis of Proline Methyl Ester Enantiomers (N-Acetyl Derivatives) on Astec® CHIRALDEX™ G-TA, suitable for GC

G005101

GC Analysis of Proline Methyl Ester Enantiomers (N-Trifluoroacetyl Derivatives) on Astec® CHIRALDEX™ G-TA, suitable for GC

G005076

GC Analysis of Verbenone Enantiomers on Astec® CHIRALDEX™ G-TA, suitable for GC

G005098

GC Analysis of Wieland-Miescher Ketone Enantiomers on Astec® CHIRALDEX™ G-TA, suitable for GC

G005111

GC Analysis of α-Hexachlorocyclohexane (α-HCH) Enantiomers on Astec® CHIRALDEX™ G-TA, suitable for GC

G005146

GC Analysis of δ-Decanolactone Enantiomers on Astec® CHIRALDEX™ G-TA, suitable for GC

G006117

GC Analysis of Volatile Flavor Compound Enantiomers on Astec® CHIRALDEX™ G-TA, suitable for GC

G006154

GC Analysis of D-Carvone Enantiomer in Caraway Essential Oil on Astec® CHIRALDEX™ G-TA, suitable for GC

G006155

GC Analysis of D-Carvone Enantiomer in Dill Seed Essential Oil on Astec® CHIRALDEX™ G-TA, suitable for GC

G006156

GC Analysis of D & L-Carvone Enantiomers in Caraway Essential Oil (Spiked with L-Carvone Enantiomer) on Astec® CHIRALDEX™ G-TA, suitable for GC

G006157

GC Analysis of D & L-Carvone Enantiomers in Dill Seed Essential Oil (Spiked with L-Carvone Enantiomer) on Astec® CHIRALDEX™ G-TA, suitable for GC

G006158

GC Analysis of D & L-Carvone Enantiomers in Native Spearmint Essential Oil (Spiked with D-Carvone Enantiomer) on Astec® CHIRALDEX™ G-TA, suitable for GC

G006159

GC Analysis of D & L-Carvone Enantiomers in Scotch Spearmint Essential Oil (Spiked with D-Carvone Enantiomer) on Astec® CHIRALDEX™ G-TA, suitable for GC

G006160

GC Analysis of D & L-Carvone Enantiomers on Astec CHIRALDEX™ G-TA, suitable for GC

G006162

GC Analysis of L-Carvone Enantiomer in Scotch Spearmint Essential Oil on Astec® CHIRALDEX™ G-TA, suitable for GC

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Certificados de análisis (COA)

Lot/Batch Number
293710-04
293710-03
293710-02
293710-01
293707-04

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Bert van Loo et al.
Chemistry & biology, 11(7), 981-990 (2004-07-24)
The enantioselectivity of epoxide hydrolase from Agrobacterium radiobacter (EchA) was improved using error-prone PCR and DNA shuffling. An agar plate assay was used to screen the mutant libraries for activity. Screening for improved enantioselectivity was subsequently done by spectrophotometric progress
Jung-Hee Woo et al.
Applied microbiology and biotechnology, 76(2), 365-375 (2007-06-02)
Previously, we reported that ten strains belonging to Erythrobacter showed epoxide hydrolase (EHase) activities toward various epoxide substrates. Three genes encoding putative EHases were identified by analyzing open reading frames of Erythrobacter litoralis HTCC2594. Despite low similarities to reported EHases
Asymmetric ring opening of meso-epoxides with B-halobis(2-isocaranyl)boranes 2-dIcr2BX
Roy, Chandra D., Brown, Herbert C.
Tetrahedron Asymmetry, 17 (13), 1931-1936 (2006)
Kinetic resolutions concentrate the minor enantiomer and aid measurement of high enantiomeric purity.
Caron, Gaetan; Tseng, George W.M.; Kazlauskas, R.J.
Tetrahedron Asymmetry, 5 (1), 83-92 (1994)
Hugo L van Beek et al.
FEBS open bio, 4, 168-174 (2014-03-22)
Enzyme stability is an important parameter in biocatalytic applications, and there is a strong need for efficient methods to generate robust enzymes. We investigated whether stabilizing disulfide bonds can be computationally designed based on a model structure. In our approach
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Chromatograms

suitable for GCsuitable for GCsuitable for GCsuitable for GCMostrar más

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