58220-U
SUPELCOSIL™ LC-8 (5 µm) HPLC Columns
L × I.D. 15 cm × 4.6 mm, HPLC Column
Sinónimos:
LC-8 Reverse-Phase HPLC Column
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About This Item
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
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product name
Columna para HPLC SUPELCOSIL™ LC-8, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
material
stainless steel column
agency
suitable for USP L7
product line
SUPELCOSIL™
feature
endcapped
packaging
1 ea of
extent of labeling
6.0% carbon loading
parameter
≤70 °C temp. range
technique(s)
HPLC: suitable
L × I.D.
15 cm × 4.6 mm
surface area
170 m2/g
surface coverage
surface coverage 3.2 μmol/m2
matrix
silica gel, spherical particle platform
fully porous particle
matrix active group
C8 (octyl) phase
particle size
5 μm
pore size
120 Å
pH range
2-7.5
application(s)
food and beverages
separation technique
reversed phase
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General description
A phase less hydrophobic than C18. Provides less retention of both polar and non-polar compounds than C18. Use a mobile phase containing 5% less organic modifier for the C8 column than C18. Polar compounds are, relatively, more strongly retained on C8 than C18 columns.
Application
- Chromatographic behaviour of ionic liquid cations in view of quantitative structure-retention relationship.: This study explores the chromatographic behavior of ionic liquid cations using quantitative structure-retention relationships (QSRR). The SUPELCOSIL™ LC-8 HPLC Column was utilized to analyze retention data for various ionic liquids, providing insights into their separation mechanisms and potential applications in analytical chemistry (Molíková et al., 2010).
- Liquid chromatographic method for the determination of lidocaine and monoethylglycine xylidide in human serum containing various concentrations of bilirubin for the assessment of liver function.: The research presents a liquid chromatographic method using the SUPELCOSIL™ LC-8 HPLC Column to determine lidocaine and its metabolite in human serum. This method is particularly useful for assessing liver function by measuring drug metabolism (Piwowarska et al., 2004).
- LC determination of morphine and morphine glucuronides in human plasma by coulometric and UV detection.: The research describes a method for the determination of morphine and its glucuronides in human plasma. Utilizing the SUPELCOSIL™ LC-8 HPLC Column, the study demonstrates the method′s sensitivity and applicability in pharmaceutical analysis (Ary et al., 2001).
Legal Information
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Application
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Descripción
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Guard cartridge
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related product
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Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Thomas Borch et al.
Journal of chromatography. A, 1022(1-2), 83-94 (2004-02-03)
Explosives such as 2,4,6-trinitrotoluene (TNT), octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX), and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) are widely distributed environmental contaminants. Complete chromatographic separation is necessary in order to accurately determine and quantify explosives and their degradation products in environmental samples and in (bio)transformation studies. The
Jadwiga Piwowarska et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 805(1), 1-5 (2004-04-29)
A high-performance liquid chromatographic method is described for determination of lidocaine (2-(dietyloamino)-N-(2,6-dimetylofenylo) acetamid) and its metabolite, monoethylglycine xylidide (MEGX), in human serum containing various concentration of bilirubin. Lidocaine and its metabolite were extracted from human serum using dichloromethane. After separation
P K Kunicki
Journal of chromatography. B, Biomedical sciences and applications, 750(1), 41-49 (2001-02-24)
A HPLC-UV determination of clobazam and N-desmethylclobazam in human serum and urine is presented. After simple liquid-liquid extraction with dichloromethane the compounds and an internal standard diazepam were separated on a Supelcosil LC-8-DB column at ambient temperature under isocratic conditions
F Belal et al.
Journal of pharmaceutical and biomedical analysis, 24(3), 335-342 (2001-02-24)
A simple, rapid and sensitive HPLC method has been developed for the simultaneous determination of ramipril and hydrochlorothiazide in their dosage forms. Acetonitrile: sodium perchlorate solution (0.1 M) adjusted to pH 2.5+/-0.2 with phosphoric acid (46:54 v/v), was used as
M Molíková et al.
Journal of chromatography. A, 1217(8), 1305-1312 (2010-01-12)
The availability of ionic liquids (ILs) in wide areas of application often results in the requirement on their determination. The attention is also often focused on the knowledge of hydrophobicity as it plays a key role in the biological effects
Chromatograms
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