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T9778

Sigma-Aldrich

Tropicamide

solid

Sinónimos:

N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide, Ro 1-7683

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About This Item

Fórmula empírica (notación de Hill):
C17H20N2O2
Número de CAS:
1508-75-4
Peso molecular:
284.35
Número CE:
216-140-2
Número MDL:
MFCD00058580
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
24277879
NACRES:
NA.77

Formulario

solid

Nivel de calidad

100

color

white

solubilidad

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 4.3 mg/mL
ethanol: 5.6 mg/mL
H2O: insoluble

temp. de almacenamiento

2-8°C

cadena SMILES

CCN(Cc1ccncc1)C(=O)C(CO)c2ccccc2

InChI

1S/C17H20N2O2/c1-2-19(12-14-8-10-18-11-9-14)17(21)16(13-20)15-6-4-3-5-7-15/h3-11,16,20H,2,12-13H2,1H3

Clave InChI

BGDKAVGWHJFAGW-UHFFFAOYSA-N

Información sobre el gen

human ... CHRM3(1131) , CHRM4(1132)

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Aplicación

Tropicamide has been used for studying the regulation of fragile X behavior in male mice. 1% tropicamide has also been used for dilating mice pupils.

Acciones bioquímicas o fisiológicas

M4 muscarinic acetylcholine receptor antagonist.

Características y beneficios

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Envase

Bottomless glass bottle. Contents are inside inserted fused cone.

Nota de preparación

Tropicamide is soluble in 45% (w/v) aqueous 2-hydroxypropyl-beta-cyclodextrin (4.3 mg/mL) and ethanol (5.6 mg/mL).

Pictogramas

Exclamation mark
GHS07

Palabra de señalización

Warning

Clasificaciones de peligro

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Órganos de actuación

Respiratory system

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
BCCJ5525
BCCB7637
BCBW0951
BCBV8350
BCBV9503

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Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

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Visite la Librería de documentos

Surabi Veeraragavan et al.
Behavioral neuroscience, 125(5), 783-790 (2011-09-29)
Muscarinic acetylcholine receptors (mAChR) are G protein-coupled receptors (M1-M5), grouped together into two functional classes, based on their G protein interaction. Although ubiquitously expressed in the CNS, the M4 protein shows highest expression in the neostriatum, cortex, and hippocampus. Electrophysiological
Raghavan Lavanya et al.
Ophthalmology, 119(3), 474-480 (2011-11-29)
To evaluate the risk of primary acute angle closure (AAC), changes in intraocular pressure (IOP), and associated risk factors after pupil dilation in Asian subjects with narrow angles (primary angle-closure suspects [PACS]). Prospective clinical study. A total of 471 subjects
Shanu Markand et al.
Investigative ophthalmology & visual science, 56(4), 2684-2695 (2015-03-15)
Methylenetetrahydrofolate reductase (Mthfr) is a key enzyme in homocysteine-methionine metabolism. We investigated Mthfr expression in retina and asked whether mild hyperhomocysteinemia, due to Mthfr deficiency, alters retinal neurovascular structure and function. Expression of Mthfr was investigated at the gene and
Tin A Tun et al.
Investigative ophthalmology & visual science, 56(5), 3337-3344 (2015-05-30)
To characterize an optical coherence tomography (OCT)-derived parameter, Bruch's membrane opening-minimum rim width (BMO-MRW), and its association with demographic and clinical parameters in normal Chinese subjects. Right eyes of 466 consecutive healthy subjects from a population-based study of Singaporean Chinese
Kyoungmin Park et al.
The American journal of pathology, 178(2), 688-698 (2011-02-02)
Pigment epithelium-derived factor (PEDF) is a serine proteinase inhibitor with antiangiogenic activities. To investigate whether PEDF overexpression has an impact on ocular neovascularization in vivo, we generated PEDF transgenic (PEDF-Tg) mice that ubiquitously express human PEDF driven by the β-actin
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