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Merck

T3651

Sigma-Aldrich

Anti-Tropomyosin antibody produced in rabbit

whole antiserum

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

contains

15 mM sodium azide

species reactivity

chicken

technique(s)

indirect immunofluorescence: 1:40 using cultured chicken fibroblasts
western blot: suitable

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

chicken ... TPM1(396366)

General description

Tropomyosin is a rigid, rod shaped protein, closely associated with actin filaments. In non-muscle cells grown in culture, tropomyosin is distributed periodically along the length of the stress fibers.

Specificity

The antibody specifically reacts with tropomyosin (typical banded pattern of stress fibers) in cultured cells and two tropomyosin bands of total chicken gizzard extract by immunoblotting.

Immunogen

smooth muscle tropomyosin from chicken gizzard.

Application

Anti-Tropomyosin antibody produced in rabbit has been used in western immunoblotting and immunofluorescence.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Differentiation of CD45?/CD31+ lung side population cells into endothelial and smooth muscle cells in vitro
Xu Y, et al.
International Journal of Molecular Medicine, 43(3), 1128-1138 (2019)
K Miyado et al.
Biochemical and biophysical research communications, 225(2), 427-435 (1996-08-14)
Tropomyosin is an actin-associated cytoskeletal protein expressed in muscle and non-muscle cells. There are several tropomyosin isoforms, and their cellular expression is known to be associated with transformation events caused by retroviral infection and chemical mutagens. We found that expression
Fang Wang et al.
Journal of biomedicine & biotechnology, 2011, 435271-435271 (2011-12-22)
Familial hypertrophic cardiomyopathy (FHC) is a disease of cardiac sarcomeres. To identify molecular mechanisms underlying FHC pathology, functional and structural differences in three FHC-related mutations in recombinant α-Tm (V95A, D175N, and E180G) were characterized using both conventional and modified in
Jürg P F Nüesch et al.
Journal of virology, 80(10), 4729-4739 (2006-04-28)
During a productive infection, the prototype strain of the parvovirus minute virus of mice (MVMp) induces dramatic morphological alterations in permissive A9 fibroblasts, culminating in cell lysis at the end of infection. These cytopathic effects (CPE) result from rearrangements and
Jürg P F Nüesch et al.
Proceedings of the National Academy of Sciences of the United States of America, 104(30), 12482-12487 (2007-07-20)
Autonomous parvoviruses induce severe morphological and physiological alterations in permissive host cells, eventually leading to cell lysis and release of progeny virions. Viral cytopathic effects (CPE) result from specific rearrangements and destruction of cytoskeletal micro- and intermediate filaments. We recently

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