T1816

Anti-Tumor Necrosis Factor-α antibody produced in goat

affinity isolated antibody, lyophilized powder

• Sinónimos: Anti-TNF-α
• UNSPSC Code: 51111800
• NACRES: NA.41

Propiedades

• biological source: goat
• Quality Level: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: pig
• technique(s): immunohistochemistry: 15 μg/mL; indirect ELISA: 0.5-1.0 μg/mL; neutralization: suitable; western blot: 0.1-0.2 μg/mL
• UniProt accession no.: P23563
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: pig ... TNF(397086)

Descripción

General description

Tumor Necrosis Factor-α (TNF-α) also refers as cachectin is a cytokine produced in response to immunological challenges such as bacteria (lipopolysaccharides), parasites, mitogens, viruses and other cytokines. It has essential roles in antitumor activity, inflammation, septic shock, immune modulation, anorexia, cachexia, hematopoiesis and viral replication. It also facilitates the growth of human fibroblasts, collagenase production as well as can activates polymorphonuclear neutrophils and osteoclasts. Anti-Tumor Necrosis Factor-α antibody can be used in neutralization and immunoblotting (working concentration-0.1-0.2 μg/ml) for detecting porcine TNF-α. Goat anti-Tumor Necrosis Factor-α antibody reacts specifically with recombinant porcine tumor necrosis factor α.

Specificity

The antibody neutralizes the biological activity of recombinant porcine TNF-α.

Immunogen

recombinant porcine TNF-α expressed in Escherichia coli.

Application

Anti-Tumor Necrosis Factor-α antibody can be used in immunohistochemistry and indirect ELISA.

Physical form

Lyophilized from a 0.2 μm filtered solution of phosphate buffered saline.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Storage Class: 10 - Combustible liquids