SRP8026
Annexin V human
recombinant, expressed in E. coli, GST tagged, ≥95% (SDS-PAGE)
Sinónimos:
Annexin A5, Calphobindin I, EC 2.7.1.23, Endonexin II, Placental anticoagulantprotein I
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About This Item
Código UNSPSC:
12352200
NACRES:
NA.32
En este momento no podemos mostrarle ni los precios ni la disponibilidad
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origen biológico
human
recombinante
expressed in E. coli
etiqueta
GST tagged
Ensayo
≥95% (SDS-PAGE)
Formulario
lyophilized
mol peso
~52 kDa
envase
pkg of 100 μg
condiciones de almacenamiento
avoid repeated freeze/thaw cycles
técnicas
activity assay: suitable
color
white
Nº de acceso UniProt
Condiciones de envío
wet ice
temp. de almacenamiento
−20°C
Información sobre el gen
human ... ANXA5(308)
Descripción general
Annexin V is a member of the annexin family of calcium and membrane-binding proteins that have anticoagulatory and anti-inflammatory properties. The encoded protein is 320 amino acid long and is folded into four domains, each having five α-helices, forming a superhelical globular structure. The ANX5 gene is mapped to human chromosome 4q26-q28 and spans a length of 28kb containing 13 exons and 12 introns.[1][2]
Aplicación
Annexin V has been used to examine phosphorylation activity of ChaK1 (channel-kinase 1).[3]
Acciones bioquímicas o fisiológicas
Annexins are a family of water-soluble proteins that bind to membranes and phospholipids in a calcium-dependent manner. They participate in several cellular functions, such as membrane fusion and cytoskeletal interaction. Annexin V is a potent anticoagulant and serves as a voltage-gated calcium channel when bound to membrane in vitro. It is found to inhibit phospholipase A2 and protein kinase C.[1][2][4]
Forma física
Lyophilized from PBS, pH 7.4.
Reconstitución
Reconstitute with 100 μL deionized water.
Otras notas
Recombinant human annexin V fused to a GST-tag.
Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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