SML1460

SAMS Peptide trifluoroacetate salt

≥95% (HPLC)

• Sinónimos: HMRSAMSGLHLVKRR trifluoroacetate salt, His-Met-Arg-Ser-Ala-Met-Ser-Gly-Leu-His-Leu-Val-Lys-Arg-Arg-OH trifluoroacetate salt, L-Histidyl-L-methionyl-L-arginyl-L-seryl-L-alanyl-L-methionyl-L-seryl-glycyl-L-leucyl-L-histidyl-L-leucyl-L-valyl-L-lysyl-L-arginyl-L-arginine trifluoroacetate salt
• Fórmula empírica (notación de Hill): C₇₄H₁₃₁N₂₉O₁₈S₂ · xC₂HF₃O₂
• Número de CAS: 125911-68-4
• Peso molecular: 1779.15 (free base basis)
• UNSPSC Code: 12352200
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥95% (HPLC)
• form: powder
• color: white to off-white
• storage temp.: −20°C
• InChI: 1S/C74H131N29O18S2/c1-38(2)27-51(66(115)100-53(30-43-32-84-37-90-43)67(116)99-52(28-39(3)4)68(117)103-57(40(5)6)70(119)97-45(15-10-11-21-75)61(110)95-46(16-12-22-85-72(77)78)62(111)98-50(71(120)121)18-14-24-87-74(81)82)92-56(106)33-88-60(109)54(34-104)101-65(114)48(19-25-122-8)93-58(107)41(7)91-69(118)55(35-105)102-63(112)47(17-13-23-86-73(79)80)96-64(113)49(20-26-123-9)94-59(108)44(76)29-42-31-83-36-89-42/h31-32,36-41,44-55,57,104-105H,10-30,33-35,75-76H2,1-9H3,(H,83,89)(H,84,90)(H,88,109)(H,91,118)(H,92,106)(H,93,107)(H,94,108)(H,95,110)(H,96,113)(H,97,119)(H,98,111)(H,99,116)(H,100,115)(H,101,114)(H,102,112)(H,103,117)(H,120,121)(H4,77,78,85)(H4,79,80,86)(H4,81,82,87)/t41-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,57-/m0/s1
• InChI key: YJAHUEAICBOBTC-CSVPVIMBSA-N

Descripción

General description

SAMS Peptide trifluoroacetate salt is a peptide having a putative AMPK phosphorylation site (Ser568) of carbohydrate-responsive element-binding protein (ChREBP) and a peptide containing a cAMP-dependent protein kinase (PKA) phosphorylation site (Thr666).

Biochem/physiol Actions

SAMS Peptide is a synthetic substrate selective for AMP-activated protein kinase (AMPK). Its sequence is based on acetyl-CoA carboxylase, which is phosphorylated exclusively by the AMPK, but with serine (Ser)-79 replaced by alanine SAMS peptide is more specific for AMPK than acetyl-CoA carboxylase itself.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable