SML0243

ML169

≥98% (HPLC)

• Sinónimos: 2-[[1-[(5-Bromo-2-fluorophenyl)methyl]-1H-indol-3-yl]sulfonyl]-N-(5-methyl-3-isoxazolyl)-acetamide, VU0405652
• Fórmula empírica (notación de Hill): C₂₁H₁₇BrFN₃O₄S
• Número de CAS: 1222878-02-5
• Peso molecular: 506.34
• Número MDL: MFCD23704785
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 329825253
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥98% (HPLC)
• Formulario: powder
• color: white to beige
• solubilidad: DMSO: >5 mg/mL
• temp. de almacenamiento: 2-8°C
• cadena SMILES: Cc1cc(NC(=O)CS(=O)(=O)c2cn(Cc3cc(Br)ccc3F)c4ccccc24)no1
• InChI: 1S/C21H17BrFN3O4S/c1-13-8-20(25-30-13)24-21(27)12-31(28,29)19-11-26(18-5-3-2-4-16(18)19)10-14-9-15(22)6-7-17(14)23/h2-9,11H,10,12H2,1H3,(H,24,25,27)
• Clave InChI: RUYRNYRGPSAXTK-UHFFFAOYSA-N

Descripción

Acciones bioquímicas o fisiológicas

ML169 is a positive allosteric modulator (PAM) of the muscarinic acetylcholine receptor M1 (CHRM1). ML169 does not cross react with other muscarinic receptors and is able to penetrate the blood brain barrier.

ML169 is a positive allosteric modulator of muscarinic acetylcholine receptor M1.

Características y beneficios

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable