SML0041

Batimastat

≥98% (HPLC), powder, matrix metalloproteinase inhibitor

• Sinónimos: BB-94; (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide
• Fórmula empírica (notación de Hill): C₂₃H₃₁N₃O₄S₂
• Número de CAS: 130370-60-4
• Peso molecular: 477.64
• MDL number: MFCD00866533
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825111
• NACRES: NA.77

Propiedades

• product name: Batimastat, ≥98% (HPLC)
• assay: ≥98% (HPLC)
• form: powder
• color: white to tan
• solubility: DMSO: ≥15 mg/mL
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSc2cccs2)C(=O)NO
• InChI: 1S/C23H31N3O4S2/c1-15(2)12-17(18(22(28)26-30)14-32-20-10-7-11-31-20)21(27)25-19(23(29)24-3)13-16-8-5-4-6-9-16/h4-11,15,17-19,30H,12-14H2,1-3H3,(H,24,29)(H,25,27)(H,26,28)/t17-,18+,19+/m1/s1
• InChI key: XFILPEOLDIKJHX-QYZOEREBSA-N

Descripción

Application

Batimastat has been used to inhibit matrix metalloproteinases (MMPs) activity in various studies.

Biochem/physiol Actions

Batimastat is hydroxamate-type inhibitor of matrix metalloproteinases (MMP). It inhibits the growth and spread of lung tumors, breast cancer regrowth and human colon tumor growth and spread in mouse models. Batimastat reduces MMP-mediated vascular dysfunction and vessel wall damage and enhances the sealing ability and bond strength of dental adhesives.

Batimastat is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable