SAB4700170

Monoclonal Anti-CD38 antibody produced in mouse

clone HIT2, purified immunoglobulin, buffered aqueous solution

• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• conjugado: unconjugated
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: HIT2, monoclonal
• Formulario: buffered aqueous solution
• reactividad de especies: human
• concentración: 1 mg/mL
• técnicas: flow cytometry: suitable
• isotipo: IgG1
• Nº de acceso NCBI: NM_001775.2
• Nº de acceso UniProt: P28907
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CD38(952)

Descripción

Descripción general

The antibody HIT2 reacts with CD38 (T10), a 45 kDa type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes; it is an antigenic marker of lymphoid cells.

Inmunógeno

Human thymocytes in foetus

Aplicación

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 2-8 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Acciones bioquímicas o fisiológicas

Cluster of differentiation 38 (CD38) controls the release of oxytocin hormone that regulates social cognition and affiliative behaviors. CD38 serves as a receptor, an ectoenzyme and acts as a highly conserved calcium-signaling molecule while functioning as a secondary messenger. The generation of cyclic Adenosine diphosphate-ribose and nicotinic acid adenine dinucleotide phosphate from NAD⁺ and NAD phosphate by ADP-ribosyl cyclase is catalyzed by CD38. The formation of adenosine is an important function of CD38. The pleiotropic nucleoside adenosine formed, acts as a regulator of immune functions and inflammation process.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable