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Key Documents

SAB4501330

Sigma-Aldrich

Anti-GSK3 antibody produced in rabbit

affinity isolated antibody

Sinónimos:

Factor A, GSK-3 α, GSK3-α, Glycogen synthase kinase-3 α, kinase GSK3-α

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 50 kDa

species reactivity

mouse, human, rat

concentration

~1 mg/mL

technique(s)

ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GSK3A(2931)

General description

GSK3A (glycogen synthase kinase 3 α) is a multifunctional protein serine kinase, that is mapped to human chromosome 19q13.

Immunogen

The antiserum was produced against synthesized peptide derived from human GSK3 alpha/beta.

Immunogen Range: 246-295

Biochem/physiol Actions

GSK3A (glycogen synthase kinase 3 α) controls multiplication, migration and cell death. It participates in the WNT and PI3K (phosphoinositide 3-kinase) signalling pathways. This protein also modulates glucose levels, inflammation and immune responses.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Population-based linkage analysis of schizophrenia and bipolar case-control cohorts identifies a potential susceptibility locus on 19q13
Francks C, et al.
Molecular Psychiatry, 15(3), 319-325 (2010)
Rahul Bhattacharjee et al.
Biology of reproduction, 92(3), 65-65 (2015-01-09)
The signaling enzyme glycogen synthase kinase 3 (GSK3) exists as two isoforms-GSK3A and GSK3B. Protein phosphorylation by GSK3 has important signaling roles in several cells. In our past work, we found that both isoforms of GSK3 are present in mouse

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