SAB4500130

Anti-Centromeric Protein A antibody produced in rabbit

affinity isolated antibody

• Sinónimos: CENA, CENP-A, CENPA, Centromere autoantigen A, Centromere protein A
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• conjugado: unconjugated
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• Formulario: buffered aqueous solution
• mol peso: antigen 15 kDa
• reactividad de especies: human
• concentración: ~1 mg/mL
• técnicas: ELISA: 1:10000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100
• Nº de acceso NCBI: P49450
• Nº de acceso UniProt: P49450
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CENPA(1058)

Descripción

Descripción general

Anti-Centromeric protein A Antibody detects endogenous levels of total Centromeric protein A protein.

Centromeric Protein A (CENPA), is encoded by the gene mapped to human chromosome 2p23.3. The encoded protein is a longer variant of histone H3 in humans.

Inmunógeno

The antiserum was produced against synthesized peptide derived from human Centromeric Protein A.

Immunogen Range: 1-50

Acciones bioquímicas o fisiológicas

Centromeric Protein A (CENPA) plays a vital role in centromere specification and facilitates its mitotic function and epigenetic maintenance. CENP-A-nucleosome associated complex (NAC) is implicated in the regulation of chromosome congression and spindle bipolarity. Disorganization of this complex leads to change in chromosome alignment and segregation that prevent cell survival regardless of continued centromere-derived mitotic checkpoint signaling.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable