SAB3700145

Anti-Horse IgG (Fc specific)-Peroxidase antibody produced in goat

affinity isolated antibody, lyophilized powder

• Sinónimos: HRP
• Código UNSPSC: 12352203
• NACRES: NA.46

Propiedades

• origen biológico: goat
• conjugado: peroxidase conjugate
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: secondary antibodies
• clon: polyclonal
• Formulario: lyophilized powder
• reactividad de especies: horse
• técnicas: immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• modificación del objetivo postraduccional: unmodified

Descripción

Descripción general

The immunoglobulin IgG from horse comprises six subtypes. The subtypes share high sequence homology. Immunoglobulin super-family have a common structure, comprising two heavy (H) chains and two light (L) chains, held together by disulfide linkages. The heavy chain has one variable N-terminal region and three to four constant (CH1-CH4) C-terminal regions. The L chain comprises of one variable N-terminal region and a constant C-terminal region.

Especificidad

This product was prepared from monospecific antiserum by immunoaffinity chromatography using Horse IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Peroxidase, Anti-Goat Serum, Horse IgG, Horse IgG F(c) and Horse Serum. No reaction was observed against Horse IgG F(ab′)2.

Inmunógeno

Horse IgG F(c) fragment

Acciones bioquímicas o fisiológicas

Immunoglobulin IgG digestion by papain results in the generation of fragment antigen binding (Fab). Pepsin digestion of IgG generates fragment crystallisable (Fc). The Fc region of IgG antibody has enormous therapeutic potential and is exploited for the development of therapeutic antibodies. Normal serum IgG levels (400-800 mg/dl) along with total serum proteins and serum globulin is essential in foals to alleviate the risk of developing failure of transfer of passive immunity(FTPI).

Propiedades físicas

Antibody format: IgG

Forma física

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Reconstitución

Reconstitute with 1.0 mL deionized water (or equivalent).

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H317
• Consejos de prudencia: P280
• Clasificaciones de peligro: Skin Sens. 1
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable