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RAB1038

Sigma-Aldrich

Human ECM-1 ELISA Kit

for cell culture supernatants, plasma, and serum samples

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About This Item

Código UNSPSC:
41116158
NACRES:
NA.32

reactividad de especies

human

envase

kit of 96 wells (12 strips x 8 wells)

técnicas

ELISA: suitable

entrada

sample type plasma
sample type cell culture supernatant(s)
sample type serum sample(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 24 pg/ml

método de detección

colorimetric

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

Información sobre el gen

human ... ECM1(1893)

Descripción general

Extracellular matrix protein 1 (ECM1) is a glycoprotein. It is expressed in skin and other tissues. The gene encoding this protein is localized on human chromosome 1q21.2.
This ELISA antibody pair detects Human Extracellular Matrix Protein 1 (ECM1)

Aplicación

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Acciones bioquímicas o fisiológicas

Extracellular matrix protein 1 (ECM1) has a role in cell proliferation, mineralization and angiogenesis. The protein has been shown to have a role in cancer invasion and progression. It is associated with hepatocellular carcinoma. Mutations in the ECM1 gene have been linked to lipoid proteinosis. The protein also promotes the Warburg effect, which is an oncogenic switch that allows cancerous cells to take in more glucose than non-cancerous cells.

Otras notas

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Pictogramas

Corrosion

Palabra de señalización

Warning

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Met. Corr. 1

Código de clase de almacenamiento

8A - Combustible corrosive hazardous materials

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Visite la Librería de documentos

Extracellular matrix protein 1 gene (ECM1) mutations in nine Iranian families with lipoid proteinosis
Izadi F, et al.
The Indian Journal of Medical Research, 143(3), 303-303 (2016)
Megan E Grund et al.
PloS one, 15(11), e0242593-e0242593 (2020-11-24)
Bacterial efflux pumps are an important pathogenicity trait because they extrude a variety of xenobiotics. Our laboratory previously identified in silico Burkholderia collagen-like protein 8 (Bucl8) in the hazardous pathogens Burkholderia pseudomallei and Burkholderia mallei. We hypothesize that Bucl8, which
Kyung-Eun Lee et al.
International journal of molecular sciences, 21(22) (2020-11-14)
In recent years, a number of active materials have been developed to provide anti-aging benefits for skin and, among them, peptides have been considered the most promising candidate due to their remarkable and long-lasting anti-wrinkle activity. Recent studies have begun
Alee Choi et al.
International journal of molecular sciences, 21(17) (2020-09-03)
Extracellular matrix (ECM) components play an important role in maintaining skeletal muscle function, but excessive accumulation of ECM components interferes with skeletal muscle regeneration after injury, eventually inducing fibrosis. Increased oxidative stress level caused by dystrophin deficiency is a key
Cristina Bárcena et al.
EBioMedicine, 43, 513-524 (2019-05-12)
Chronic hepatic inflammation leads to liver fibrosis, which may progress to cirrhosis, a condition with high morbidity. Our aim was to assess the as yet unknown role of innate immunity protein CD5L in liver fibrosis. CD5L was measured by ELISA

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