RAB0695
Human IL21 / Interleukin-21 ELISA Kit
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About This Item
Código UNSPSC:
41116158
NACRES:
NA.32
Productos recomendados
reactividad de especies
human
envase
kit of 96 wells (12 strips x 8 wells)
técnicas
ELISA: suitable
entrada
sample type serum
sample type plasma
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 110 pg/mL
standard curve range: 125-8000 pg/mL
método de detección
colorimetric
Condiciones de envío
wet ice
temp. de almacenamiento
−20°C
Información sobre el gen
human ... IL21(59067)
Descripción general
Interleukin-21 (IL-21) is a pleiotropic cytokine. It belongs to the common γ-chain cytokines with broad pleiotropic actions. This gene is located on human chromosome 4q27.
Aplicación
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Acciones bioquímicas o fisiológicas
Interleukin-21 (IL-21) regulates chronic viral infection, thereby plays a major role for immune responses in a mouse model of HBV (hepatitis B virus) infection. This gene is linked to celiac disease, rheumatoid arthritis (RA), type 1 diabetes mellitus (type 1 DM) and psoriatic arthritis. IL-21 has the ability to promote maturation and increase the cytotoxicity of CD8+ T cells and natural killer (NK) cells.
The antibody pair provided in this kit recognizes Human Interleukin-21.
Otras notas
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Met. Corr. 1
Código de clase de almacenamiento
8A - Combustible corrosive hazardous materials
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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Association of the autoimmunity locus 4q27 with juvenile idiopathic arthritis
Albers HM, et al.
Arthritis and Rheumatism, 60(3), 60(3)-60(3) (2009)
Identification of the novel 3? UTR sequences of human IL-21 mRNA as potential targets of miRNAs
Enomoto Y, et al.
Scientific Reports, 7(1), 7780-7780 (2017)
Yolanda P Alemán-García et al.
Journal of immunology research, 2021, 6630715-6630715 (2021-03-26)
Systemic lupus erythematosus is characterized by high levels of IgG class autoantibodies that contribute to the pathophysiology of the disease. The formation of these autoantibodies occurs in the germinal centers, where there is cooperation between follicular T helper cells (TFH)
Induction of IL-21 in Peripheral T Follicular Helper cells is Indicator of Influenza Vaccine Response in Previously Vaccinated HIV-Infected Pediatric Cohort
de Armas LR, et al.
Journal of Immunology (2017)
Biological effects of IL-21 on different immune cells and its role in autoimmune diseases.
Gharibi T, et al.
Immunobiology, 221(2), 357-367 (2016)
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